Sökning: "Alireza Azimi"

Hittade 1 avhandling innehållade orden Alireza Azimi.

  1. 1. Unravelling molecular mechanisms underlying therapy resistance in cutaneous melanoma

    Författare :Alireza Azimi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : For many years the standard treatment of advanced metastatic melanoma with chemotherapeutic agents, including temozolomide (TMZ) and dacarbazine (DTIC), has been unsuccessful. The paradigm shift in melanoma treatment occurred with the identification of mutations in the BRAF gene that leads to a constitutively active BRAF V600E protein. LÄS MER