Sökning: "Ali receptor"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden Ali receptor.

  1. 1. HER2-receptor quantification in breast cancer patients by imaging with ABY-025 Affibody and PET

    Författare :Ali Alhuseinalkhudhur; Henrik Lindman; Jens Sörensen; Mark Lubberink; Irina Velikyan; Rimma Axelsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PET; Breast cancer; HER2; Affibody; ABY-025; Molecular imaging; Kinetic modelling; Brain metastasis;

    Sammanfattning : Breast cancer is the most common malignancy in women worldwide. Human epidermal growth factor receptor type 2 (HER2) is overexpressed in up to 20% of breast cancer cases and is considered an important prognostic factor and a therapeutic target. LÄS MER

  3. 2. Toll-like receptors (TLRs) and inflammatory bone modeling

    Författare :Ali Kassem; Ulf Lerner; Pernilla Lundberg; Pedro Souza; Timothy Arnett; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Toll-like receptor; osteoclast; osteoblast; bone resorption; bone formation; P. gingivalis; S. aureus; flagellin.;

    Sammanfattning : Patients with inflammatory or infectious conditions such as periodontitis, peri-implantitis, osteomyelitis, rheumatoid arthritis, septic arthritis and loosened joint prosthesis display varying severity of destruction in the adjacent bone tissue. Bone loss in inflammatory diseases is considered a consequence of cytokine induced RANKL and subsequent enhanced osteoclast formation. LÄS MER

  4. 3. Modulation of hormone signaling by cadmium : from molecular mechanisms to health implications

    Författare :Imran Ali; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cadmium is a toxic metal classified as human carcinogen and ubiquitously found in our environment mainly from anthropogenic activities. Exposure to cadmium has been associated with increased risk of certain hormone-dependent cancers in humans, and the metal has been proposed to possess endocrine disruptive properties by mimicking the physiological actions of estrogens. LÄS MER

  5. 4. The biological mechanisms in neutrophil and eosinophil adhesion and transmigration in vitro and theur relation to the inflammatory process in vivo

    Författare :Ali Moshfegh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In inflammatory reactions, eosinophils and neutrophils constitute the major classes of granulocytes that emigrate from the bloodstream into the tissues. The recruitment of inflammatory cells constitutes a multi-step process that includes sequential adhesion and transmigration through, the endothelial lining, the underlying basement membrane and a variety of extracellular matrix components. LÄS MER

  7. 5. B lymphocytes in solid human malignancies

    Författare :Ali Zirakzadeh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cancer remains one of the leading causes of death worldwide. Modern treatments such as immunotherapy and neoadjuvant chemotherapy exhibit promising results. However better understanding of the treatments may lead to optimizations and consequently better prognosis. LÄS MER