Sökning: "Alfonso Garcia-Bennett"

Hittade 4 avhandlingar innehållade orden Alfonso Garcia-Bennett.

  1. 1. Novel Syntheses, Structures and Functions of Mesoporous Silica Materials

    Författare :Rambabu Atluri; Alfonso E Garcia-Bennett; Maria Strömme; Paul Wright; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Materials science; Teknisk materialvetenskap; Materialvetenskap; Materials Science;

    Sammanfattning : The field of mesoporous silica has been studied for about 20 years but it is still an area attracting a lot of attention. The use of novel templating molecules and several issues related to the synthesis and fine structural details are still poorly understood. LÄS MER

  3. 2. Toxicological and Immunomodulatory Properties of Mesoporous Silica Particles : Applications in Life Sciences

    Författare :Natalia Kupferschmidt; Alfonso E Garcia-Bennett; Susanne Gabrielsson; Mika Lindén; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; mesoporous silica; biocompatibility; adjuvants; drug delivery systems; obesity;

    Sammanfattning : Mesoporous silica particles offer great potential benefits as vehicles for drug delivery and in other biomedical applications. They present a high loading capacity due their ordered and size-tuneable pores that allow molecules to be loaded and released. LÄS MER

  4. 3. Engineered core-shell nanoparticles for biomedical applications

    Författare :Carmen Mihaela Vogt; Mamoun Muhammed; Alfonso Garcia-Bennett; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Functional materials; Funktionella material;

    Sammanfattning : The necessity for synthesis of nanoparticles with well controlled size and morphology emerged with the development in recent years of novel advanced applications especially in biomedical related fields. These applications require nanoparticles with more complex architecture such as multifunctional nanoparticles (i.e. LÄS MER

  5. 4. Dissolving the Rocks : Solubility Enhancement of Active Pharmaceutical Ingredients using Mesoporous Silica

    Författare :Xin Xia; Alfonso E. Garcia-Bennett; Xiaodong Zou; Göran Frenning; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mesoporous silica; drug delivery; solubility enhancement; active pharmaceutical ingredients; oral toxicity; confinement; crystallization; pharmaceutical excipients; bioavailability; Inorganic Chemistry; oorganisk kemi;

    Sammanfattning : Poor aqueous solubility is one of the greatest barriers for new drug candidates to enter toxicology studies, let alone clinical trials. This thesis focuses on contributing to solving this problem, evaluating the oral toxicity of mesoporous silica particles, and enhancing the apparent solubility and bioavailability of active pharmaceutical ingredients in vitro and in vivo using mesoporous silica particles. LÄS MER