Sökning: "Alexandra Treschow"

Hittade 2 avhandlingar innehållade orden Alexandra Treschow.

  1. 1. Optimization of suicide gene therapy in stem cell transplantation with special reference to the selection marker OuaSelect

    Författare :Alexandra Treschow; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Gene therapy; cell selection; suicide gene; cancer; immunotherapy; viral vectors; thymidine kinase; Na ; K -ATPase;

    Sammanfattning : For many patients suffering from leukemia and other hematological malignancies, allogeneic hematopoietic stem cell transplantation (HSCT) represents the only curative approach. However, an optimal HSCT procedure is yet to be developed. Transplant-related morbidity and mortality are severe complications arising from this treatment modality. LÄS MER

  3. 2. Tolerance Mechanisms in Collagen-Induced Arthritis an Animal Model of Rheumatoid Arthritis

    Författare :Alexandra Treschow; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skeleton; Tolerance; Regulation; IFN-beta; Macrophages; Immunology; serology; transplantation; Immunologi; serologi; Arthritis; Collage; rheumatology locomotion; muscle system; Skelett; muskelsystem; reumatologi;

    Sammanfattning : Collagen-induced arthritis (CIA) is one of the most commonly used animal models for Rheumatoid arthritis (RA). CIA is induced in susceptible mouse strains after immunization with heterologous type II collagen (CII). In mice of the H-2q haplotype rat CII (rCII) is used whereas in mice of the H-2r haplotype bovine CII is utilized. LÄS MER