Sökning: "Alexander Efanov"

Hittade 1 avhandling innehållade orden Alexander Efanov.

1. 1. Stimulation of insulin secretion independently from changes in cytosolic free Ca²+-concentration : studies with imidazolines and inositol polyphosphates

   Författare :Alexander Efanov; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :insulin secretion; pancreatic ß-cell; imidazolines; inositol polyphosphates;

   Sammanfattning : Insulin secretion from the islets of Langerhans is regulated by changes in glucose concentration. Glucose stimulates secretion by two mechanisms. First, it increases cytosolic free Ca2+ concentration ([Ca2+]i) by inhibition of ATP-dependent K+-channels (KATP) and induction of membrane depolarization. LÄS MER