Sökning: "Akut"

Visar resultat 21 - 25 av 277 avhandlingar innehållade ordet Akut.

1. 21. Impact of Risk Factors and Treatment in Coronary Heart Disease

   Författare :Lena Björck; Göteborgs universitet; []
   Nyckelord :coronary disease; myocardinal infarction; risk factors; smoking; lipid levels;

   Sammanfattning : Aims: The aim of the present study was to explore how risk factors and medication influence clinical presentation and mortality in coronary heart disease (CHD) and to explain how much of the decrease in CHD mortality in Sweden that could be attributed to medical and surgical treatments, and how much to changes in cardiovascular risk factors. Subjects and methods: We included 781 consecutive patients with a first acute myocardial infarction (AMI) during the period 1994 to 2002, to investigate trends in the use of lipid-lowering treatment, and changes in serum lipids. LÄS MER

3. 22. Endogenous t-PA release and pharmacological thrombolysis - Experimental animal studies of the coronary circulation

   Författare :Jan-Arne Björkman; Göteborgs universitet; []
   Nyckelord :Klinisk fysiologi;

   Sammanfattning : Abstract The physiologically most important activator of intravascular fibrinolysis is tissue-type plasminogen activator (t-PA) released from endothelial cells. In man, sympathomimetic drugs increase the systemic concentration of t-PA. LÄS MER

4. 23. Effects of oestrogen on haemodynamic and vascular reactivity - A study in animal models and humans

   Författare :Lisa Brandin; Göteborgs universitet; []
   Nyckelord :adrenergic reactivity; endothelium; haemodynamic; hypertension; oestrogen; postmenopausal women; resistance arteries; spontaneously hypertensive rats; stress;

   Sammanfattning : Effects of Oestrogen on Haemodynamic and Vascular Reactivity A study in animal models and humans Lisa Brandin Institute of Medicine, Department of Emergency and Cardiovascular Medicine, Sahlgrenska University Hospital/Östra, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden ABSTRACT Previous studies have shown that oestrogen, the female sex hormone, plays a protective role in the cardiovascular system. However the site of action remains incompletely understood. LÄS MER

5. 24. Plasminogen Activator Inhibitor 1 in Platelets - Studies of Synthesis, Activity, and Glycosylation Patterns

   Författare :Helén Brogren; Göteborgs universitet; []
   Nyckelord :PAI-1; platelets; plasma; fibrinolysis; synthesis; polymorphism; glycosylation; activity; platelet mRNA;

   Sammanfattning : Plasminogen activator inhibitor 1 (PAI-1) is the main physiological inhibitor of tissue-type plasminogen activator. Thus PAI-1 plays an important role in decreasing the fibrinolytic activity in human blood. PAI-1 is present in high concentrations in platelets and also in low concentrations in plasma, but the source of plasma PAI-1 is not known. LÄS MER

7. 25. Effects of Biomechanical Stress on Gene Regulation in Vascular Cells

   Författare :Maria Carlström; Göteborgs universitet; []
   Nyckelord :shear stress; intraluminal pressure; endothelium; gene expression; DNA microarray; real-time RT-PCR; reference genes; smooth muscle cells; P2 receptors; TNF-alpha; urokinase-type plasminogen activator;

   Sammanfattning : The vascular vessel wall is constantly exposed to biomechanical forces, such as shear and tensile stress. Biomechanical forces are important for several physiological and pathological processes and have been shown to regulate a number of fundamental vascular functions, such as vascular tone and remodeling processes. LÄS MER