Sökning: "Ahmed Waraky"

Hittade 1 avhandling innehållade orden Ahmed Waraky.

1. 1. Insulin-like growth factor 1 receptor, novel functions and future possibilities

   Författare :Ahmed Waraky; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Insulin like growth factor-1 receptor (IGF-1R) has been shown to be important for cancer cell growth and survival, and is often overexpressed in malignant and premalignant tissues. Ligand binding to IGF-1R induces transphosphorylation and activation of the receptor, leading to subsequent activation of the phosphatidyl inositol-3 kinase (PI3K), the mitogen-activated protein kinase (MAPK) and the 14-3-3 pathways. LÄS MER