Sökning: "Agouti"

Visar resultat 1 - 5 av 21 avhandlingar innehållade ordet Agouti.

  1. 1. Inferring demographic history and speciation of grouse using whole genome sequences

    Författare :Radoslav Kozma; Jacob Höglund; Jeff A. Johnson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Demographic history; speciation; effective population size; adaptation; willow grouse; red grouse; black grouse; rock ptarmigan; Tetraoninae; conservation genetics; climate change; PSMC; species distribution modelling; FOXP4; Agouti;

    Sammanfattning : From an ecological perspective, knowledge of demographic history is highly valuable because population size fluctuations can be matched to known climatic events, thereby revealing great insight into a species’ reaction to past climate change. This in turn enables us to predict how they might respond to future climate scenarios. LÄS MER

  3. 2. Neuropeptide circuitries regulating food and water intake

    Författare :Christian Broberger; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :agouti gene-related protein; anorexia mutation; arcuate nucleus; cholecystokinin; cocaine- and amphetamine-regulated transcript; coexistence; confocal microscopy; dorsal root ganglion; feeding; hypocretin; immunohistochemistry; in situ hybridization; melanin-concentrating hormone; nodose ganglion; nucleus tractus solitaxii; orexin; paraventricular nucleus; satiety; sensory neurones; pro-opiomelanocortin; vagus nerve;

    Sammanfattning : An adequate supply of nutrients through food intake is critical for survival, as evidenced by disorders such as obesity and anorexia, which in the long run may be life-threatening. Feeding behaviour is ultimately controlled by interacting neuronal populations in the brain. LÄS MER

  4. 3. Mechanisms of opiate tolerance and dependence in the rat

    Författare :Orsolya Hoffman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Drug addiction is a complex phenomenon with various biological, psychological and social causes and consequences, which belongs to the major problems of today's society. Opiates have been used and misused for thousand of years and addiction to them develops both in humans and in animals. LÄS MER

  5. 4. Prevention of Postoperative Duodenal Ileus by COX-2 Inhibition Improves Duodenal Function in Anaesthetised Rats

    Författare :John Sedin; Olof Nylander; Markus Sjöblom; Lars Fändriks; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; duodenum; motility; enteric nervous system; luminal alkalinisation; CFTR; VIP; luminal Cl-; fluid secretion; solute absorption; mucosal permeability; 51Cr-EDTA; luminal osmolality; luminal hypertonicity; glucose; mannitol; orange juice; parecoxib; hexamethonium; mecamylamine; Physiology; Fysiologi;

    Sammanfattning : Abdominal surgery inhibits gastrointestinal motility, a phenomenon referred to as postoperative ileus. Since the postoperative ileus disturbs duodenal physiology it is important to minimize the side effects of this condition. LÄS MER

  7. 5. Genetic influence on enantiomeric drug disposition : Focus on venlafaxine and citalopram

    Författare :Maria Kingbäck; Fredrik Kugelberg; Björn Carlsson; Martin Josefsson; Finn Bengtsson; Johan Ahlner; Anders Rane; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : A molecule that is not identical to its mirror image is said to be chiral. A racemic mixture, or a racemate, is one that has equal amounts of S- and R-enantiomers of a chiral molecule. Two examples of frequently prescribed racemic drugs are the antidepressants venlafaxine (VEN) and citalopram (CIT). LÄS MER