Sökning: "Agnieszka Kłosowska-wardęga"

Hittade 1 avhandling innehållade orden Agnieszka Kłosowska-wardęga.

1. 1. Combination Therapies Targeting PDGF and VEGF Signaling Pathways in Solid Tumors

   Författare :Agnieszka Kłosowska-Wardęga; Carina Hellberg; Carl-Henrik Heldin; Per Lindahl; Uppsala universitet; []
   Nyckelord :MEDICINE; MEDICIN; Oncology; Onkologi;

   Sammanfattning : Vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) are independently involved in several cancer-associated mechanisms including autocrine stimulation of cancer cells, stimulation of tumor angiogenesis and regulation of interstitial fluid pressure (IFP). The scope of this thesis was to investigate the combinatory effect of anti-VEGF and anti-PDGF treatment on tumor angiogenesis and tumor IFP. LÄS MER