Sökning: "Agneta Rannug"
Hittade 3 avhandlingar innehållade orden Agneta Rannug.
1. Formation and metabolism of the tryptophan-derived 6-formylindolo[3,2-b]carbazole - a light-induced Ah-receptor ligand
Sammanfattning : The aryl hydrocarbon receptor (AhR) is a ligand dependent transcription factor ubiquitously expressed in mammalian cells. It is a genetically ancient protein mostly known for binding the extremely toxic contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). LÄS MER
2. Direct and indirect mechanisms for aryl hydrocarbon receptor activation mediated by 6-formylindolo[3,2-b]carbazole
Sammanfattning : The aryl hydrocarbon receptor (AhR) is mostly recognized for mediating the adverse effects of dioxins. In addition, endogenous activation of the AhR seems to have important biological functions. Several studies have demonstrated an activation of the receptor when no exogenous ligand was added. LÄS MER
3. Genotoxic hazards in the rubber industry : application of short-term tests in work environment analyses
Sammanfattning : Excess mortality from a number of different types of cancer has been associated with work in the rubber industry. The aim of the present study - using short-term tests for mutagenicity - was to identify potentially hazardous additives and process fumes to which workers are exposed. LÄS MER