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Visar resultat 1 - 5 av 13 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Exotoxins of Aggregatibacter actinomycetemcomitans and periodontal attachment loss in adolescents

   Författare :Carola Höglund Åberg; Anders Johansson; Rolf Claesson; Dorte Haubek; Andrea Mombelli; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aggregatibacter actinomycetemcomitans; periodontal attachment loss; JP2 genotype; non-JP2 genotype; LtxA; Cdt; Infectious Diseases; infektionssjukdomar;

   Sammanfattning : Aggregatibacter actinomycetemcomitans is an oral bacterium that is mainly associated with aggressive forms of periodontitis, which most often starts at an early age. Amongst the virulence factors of A. LÄS MER

3. 2. Inflammatory cell death of human macrophages induced by Aggregatibacter actinomycetemcomitans leukotoxin

   Författare :Peyman Kelk; Anders Johansson; Charels A Dinarello; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aggregatibacter actinomycetemcomitans; leukotoxin; IL-1β; caspase-1; inflammatory cell death; pyroptosis; ODONTOLOGY; ODONTOLOGI; odontologi; Odontology;

   Sammanfattning : Aggregatibacter (Actinobacillus) actinomycetemcomitans is a bacterium mainly associated with aggressive forms of periodontitis. Among its virulence factors, a leukotoxin is suggested to play an important role in the pathogenicity. LÄS MER

4. 3. Vesicle-independent extracellular release and bioactivity of peptidoglycan-associated lipoprotein from Aggregatibacter actinomycetemcomitans

   Författare :Maribasappa Karched; Sirkka Asikainen; Ann-Beth Jonsson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peptidoglycan-associated lipoprotein; outer membrane proteins; immunoproteomics; periodontitis; cytokines; Aggregatibacter actinomycetemcomitans.; Oral microbiology; Oral mikrobiologi;

   Sammanfattning : Aggregatibacter (Actinobacillus) actinomycetemcomitans is a Gram-negative coccobacillus of the Pasteurellaceae family. It is implicated in periodontitis, a common low-grade bacterial infection, but it can also cause non-oral infections. The main aim of this project was to identify and characterize in A. LÄS MER

5. 4. Periodontitis in adolescents : presence of Aggregatibacter species and interactions with the host

   Författare :Mark Lindholm; Jan Oscarsson; Anders Johansson; Carola Höglund-Åberg; Eija Könönen; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aggregatibacter actinomycetemcomitans; Aggregatibacter aphrophilus; periodontitis; adolescents; OmpA; outer membrane vesicles; serum resistance; odontologi; Odontology;

   Sammanfattning : Aggregatibacter actinomycetemcomitans and Aggregatibacter aphrophilus are closely related gram-negative bacteria mainly found in the oral cavity. Periodontitis in adolescents is associated with the presence of A. actinomycetemcomitans, but not with the presence of A. aphrophilus. LÄS MER

7. 5. Vesicle-mediated and free soluble delivery of bacterial effector proteins by oral and systemic pathogens

   Författare :Bernard Thay; Jan Oscarsson; Mikael Rhen; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Periodontitis; Aggregatibacter actinomycetemcomitans; Staphylococcus aureus; membrane vesicles; vesicle-host cell interaction; protein delivery; molekylärbiologi; Molecular Biology;

   Sammanfattning : Periodontitis, the primary cause of tooth-loss worldwide, is a bacterially induced chronic inflammatory disease of the periodontium. It is associated with systemic conditions such as cardiovascular disease (CVD). However, pathogenic mechanisms of periodontitis-associated bacteria that may contribute to the CVD association are unclear. LÄS MER