Sökning: "Age of onset"

Visar resultat 16 - 20 av 614 avhandlingar innehållade orden Age of onset.

  1. 16. Factors influencing the risk of diabetic nephropathy : analyses of genes, smoking and diet

    Författare :Anna Möllsten; Gisela Dahlquist; Lise Tarnow; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; type 1 diabetes; diabetic nephropathy; oxidative stress; smoking; diet; blood pressure; renin-angiotensin system; nitric oxide synthase; Kidney diseases; Njursjukdomar;

    Sammanfattning : Diabetic long-term complications, despite intensive treatment, cause serious handicaps at relatively young age in diabetic patients. Diabetic nephropathy (DN) develops in up to 30% of patients with type 1 diabetes (T1D). LÄS MER

  2. 17. Histopathological and immunocytochemical studies in age-associated dementias : the importance of rigorous histopathological criteria for classification of progressive dementia disorders

    Författare :Irina Alafuzoff; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Dementia is an age-associated organic brain disorder, recogniz­able by the essential features of psychological or behavioral abnormality associated with permanent dysfunction of the brain interfering with social and occupational functioning.There are two clinical and three histopathological forms of dementia 1) primary degenerative dementia, (PDD), or Alzhei­mer's dementia/Senile dementia of Alzheimers type (AD/SDAT) which is associated with clinical features of uniform progres­sion and insidious onset of symptoms and histopathologically i- dentified by the occurrence of neurofibrillary tangles (NFT) and senile/neuritic plaques (SP/NP) in various cortical and subcor- tical regions; 2) vascular dementia, or multi-infarct dementia (MID), which is associated with clinical features of stepwise progress and patchy distribution of deficits, and histopatholo­gically identified by the occurrence of multiple large and/or small haemorrhagic and/or ischaemic infarcts in various cortical and subcortical regions and 3) intermediate form of dementia or "mixed” ("combined") dementia (AD-MID), which is histopatho- logically associated with the coexistance of symptoms and le­sions observed in AD/SDAT and MID, and clinically referred to the MID group. LÄS MER

  3. 18. Aspects of the etiology of gastric adenocarcinoma

    Författare :Krister Sjödahl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Stomach; gastric; cancer; etiology; epidemiology; incidence; tobacco; smoking; alcohol; dust; occupational; physical activity; BMI; body mass; overweight; salt;

    Sammanfattning : Gastric adenocarcinoma is the fourth most common malignancy and the second leading cause of cancer death in the world. Tremendous effort has been made to look into the causation of gastric cancer. Etiological research plays a key role in identifying possible preventive and interventional measures. LÄS MER

  4. 19. Demographic and clinical characteristics in groups of individual with exessive alcohol intake

    Författare :Kristina Berglund; Göteborgs universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Excessive alcohol intake; demography; clinical characteristics; substance use; age; gender; treatment experience;

    Sammanfattning : People who misuse alcohol are a heterogeneous group with different etiology and clinical characteristics. One aim in the field of alcohol research has been to categorise these individuals in order to study possible pathways into alcohol use disorders and the long-term course of alcoholism. LÄS MER

  5. 20. Towards systematic prevention of athletics injuries : Use of clinical epidemiology for evidence-based injury prevention

    Författare :Jenny Jacobsson; Toomas Timpka; Per Renström; Sverker Nilsson; Willem van Mechelen; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : The aims of this thesis were to outline the design protocol for a prospective clinical epidemiological study of injuries among athletics athletes; study the 1-year prevalence, the point prevalence and incidence of injuries in total cohorts of Swedish elite adult and talented youth athletics athletes; pinpoint the risk indicators and factors for different injury types/patterns in athletics.In paper I, an argument-based method to investigate complex design problems was used to structure the collection and analysis of data. LÄS MER