Sökning: "Age at onset genetic"
Visar resultat 1 - 5 av 139 avhandlingar innehållade orden Age at onset genetic.
1. Population genetic studies of psoriasis
Sammanfattning : Psoriasis is a genetically determined, common skin disease affecting about 3 % of the population. The inheritance pattern has earlier been unclear. In collaboration with the Swedish Psoriasis Association, we have collected information on the occurrence of psoriasis in the families of 11,366 members of the Association. LÄS MER
2. Breast cancer in young women. Aspects of heredity and contralateral disease
Sammanfattning : Breast cancer is the most commonly diagnosed cancer among women in Sweden, as well as worldwide. In Sweden, 8,288 women were diagnosed with invasive breast cancer in 2019, out of whom approximately 1.5% were younger than 35 years of age. LÄS MER
3. Pathophysiological and clinical studies on Crohn's disease in children
Sammanfattning : Crohn’s disease (CD) is often diagnosed in late childhood and early adulthood. Clinical findings include abdominal pain, diarrhea, rectal bleeding, perianal lesions, weight loss and growth retardation. Extra-intestinal manifestations, strictures and fistulas may complicate the disease. LÄS MER
4. Genetic Studies of Alzheimer's Disease
Sammanfattning : Patients with Alzheimer's disease (AD) often have a family history of the disease, implicating genetics as a major risk factor. Three genes are currently known to cause familial early-onset AD (65 years), only the APOE gene has repeatedly been associated to AD, where the ε4 allele increases disease risk and decreases age at onset. LÄS MER
5. Early rheumatoid arthritis aspects of severity and co-morbidity
Sammanfattning : Background Rheumatoid arthritis (RA) is a systemic progressive destructive joint disease with an increased risk for co-morbidity and premature death if untreated. Cardiovascular disease (CVD) is the main cause of death but also other co-morbid conditions contribute to the patient’s shorter life expectancy. LÄS MER
