Sökning: "Affymetrix"

Visar resultat 1 - 5 av 42 avhandlingar innehållade ordet Affymetrix.

  1. 1. The Human Y chromosome and its role in the developing male nervous system

    Författare :Martin M. Johansson; David Skuse; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MSY; sex differences; CNV; SNP; palindrome; palindromes; gr gr duplication; gr gr deletion; b2 b3 deletion; b2 b3 duplication; blue-grey duplication; blue-grey like duplication; IR2; U3; STS; AZFa; AZFb; AZFc; Olivary nucleus; Medulla oblongata; spinal cord; white matter; Affymetrix 6.0; embryo; embryonal; haplogroup; haplogroups; R1a; R1b; R-M207; E-M96; I-M170; J-M304; G-M201; Ashkenazi; Bolivian; Chinese; SNP array; padlock probing; AMY-tree; Biologi med inriktning mot zoologisk utvecklingsbiologi; Biology with specialization in Animal Development;

    Sammanfattning : Recent research demonstrated that besides a role in sex determination and male fertility, the Y chromosome is involved in additional functions including prostate cancer, sex-specific effects on the brain and behaviour, graft-versus-host disease, nociception, aggression and autoimmune diseases. The results presented in this thesis include an analysis of sex-biased genes encoded on the X and Y chromosomes of rodents. LÄS MER

  3. 2. Statistical analysis of variability in Affymetrix GeneChip 3.1 expression data and master equation modelling of probe-target hybridization

    Författare :Daniel Lindqvist; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  4. 3. Gene Expression Profiling of Human Atherosclerosis

    Författare :Sara Hägg; Linköpings universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : Atherosclerosis is the main underlying cause of coronary artery disease (CAD) and stroke. These two diseases are leading causes of death in the developed world. The socio-economical cost for treatments and absence of work is enormous. Recent numbers from the US show no tendency of decline in the spread of atherosclerosis. LÄS MER

  5. 4. Small Intestinal Neuroendocrine Tumor Analyses : Somatostatin Analog Effects and MicroRNA Profiling

    Författare :Su-Chen Li; Valeria Giandomenico; Kjell Öberg; Marco Volante; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Small intestinal neuroendocrine tumors; Somatostatin analogs; Laser-capture microdissection; Microarray profiling and microRNA profiling; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Sammanfattning : Small intestinal neuroendocrine tumors (SI-NETs) originate from serotonin-producing enterochromaffin (EC) cells in the intestinal mucosa. Somatostatin analogs (SSAs) are mainly used to control hormonal secretion and tumor growth. However, the molecular mechanisms leading to the control of SI-NETs are unknown. LÄS MER

  7. 5. Anti-parasitic and anti-viral immune responses in insects

    Författare :Olle Terenius; Ingrid Faye; Kenneth Söderhäll; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hemolin; Hyalophora cecropia; Antheraea pernyi; Drosophila melanogaster; anti-viral; anti-parasitic; rna interference; microarray; innate immunity; Genetics; Genetik;

    Sammanfattning : Insects encounter many microorganisms in nature and to survive they have developed counter measures against the invading pathogens. In Drosophila melanogaster research on insect immunity has mainly been focused on infections by bacteria and fungi. LÄS MER