Sökning: "Affinity Capillary Electrophoresis"
Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Affinity Capillary Electrophoresis.
1. Method development for affinity capillary electrophoresis of ß2-glycoprotein I and biological ligands
Sammanfattning : The final goal of this study is to establish a microscale analysis method that allows solution phase characterization of interactions between β2-glycoprotein I (β2gpI) and some of its ligands. Human β2gpI is a phospholipid- and heparin-binding plasma glycoprotein. LÄS MER
2. Enantiomeric separation by capillary electrophoresis : With special emphasis on the partial filling technique
Sammanfattning : Capillary electrophoresis as a powerful separation technique was employed for resolution of racemic drugs. Taurodeoxycholate (TDC), different cyclodextrins and α1- acid glycoprotein (AGP) were dissolved in the background electrolyte at low pH (3.0 to 4.0 ) as chiral selectors. LÄS MER
3. Molecularly Imprinted Matrices for Electrochromatography
Sammanfattning : This thesis deals with the combination of electrochromatography and molecular imprinting technology. Electrochromatography is characterised by high separation efficiency, simple instrumentation, and minute consumption of sample. LÄS MER
4. Enantioselective Binding of Designed Propranolol Analogues to the Cellobiohydrolase Cel7A
Sammanfattning : This thesis describes the affinity and enantiomeric selectivity of the cellobiohydrolase Cel7A (isolated from Hypocrea jercorina). The chiral recognition of the enzyme has been studied with respect to amino alcohols and new ligands have been designed, based on the structure of the common ?-blocker propranolol. LÄS MER
5. Quantitative Bioanalysis : Liquid separations coupled to targeted mass spectrometric measurements of bioactive compounds
Sammanfattning : Performing quantitative analysis of targeted bioactive compounds in biological samples, such as blood plasma, cerebrospinal fluid or extracts from pig liver, put high demands on the ruggedness of the method acquiring the results. In addition to the complexity of the sample matrix, the bioactive compounds targeted for analysis usually have low levels of natural abundance, further increasing the demand on the analytical method sensitivity. LÄS MER