Sökning: "Adverse drug reactions"

Visar resultat 16 - 20 av 76 avhandlingar innehållade orden Adverse drug reactions.

  1. 16. The use of Bayesian confidence propagation neural network in pharmacovigilance

    Författare :Andrew Bate; Umeå universitet; []
    Nyckelord :adverse drug reactions; pharmacovigilance; signal detection; spontaneous reporting; data mining; Bayesian statistics; BCPNN; neural network; medicinsk farmakologi; Medical Pharmacology;

    Sammanfattning : The WHO database contains more than 2.8 million case reports of suspected adverse drug reactions reported from 70 countries worldwide since 1968. The Uppsala Monitoring Centre maintains and analyses this database for new signals on behalf of the WHO Programme for International Drug Monitoring. LÄS MER

  2. 17. Statistical methods for knowledge discovery in adverse drug reaction surveillance

    Författare :G. Niklas Norén; Rolf Sundberg; I. Ralph Edwards; Heikki Mannila; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mathematical statistics; Matematisk statistik; Mathematical Statistics; matematisk statistik;

    Sammanfattning : Collections of individual case safety reports are the main resource for early discovery of unknown adverse reactions to drugs once they have been introduced to the general public. The data sets involved are complex and based on voluntary submission of reports, but contain pieces of very important information. LÄS MER

  3. 18. On drug use, multiple medication and polypharmacy in a national population

    Författare :Bo Hovstadius; Göran Petersson; Sven Tågerud; Bengt Åstrand; Björn Wettermark; Linnéuniversitetet; []
    Nyckelord :drug use; multiple medication; polypharmacy; register; prevalence; therapeutic intensity; acquisition cost.; NATURAL SCIENCES; NATURVETENSKAP; Biomedical Sciences; Biomedicinsk vetenskap;

    Sammanfattning : The application of multiple medications has successively increased during a number of years and has thereby increased the potential risks of adverse drug reactions, interactions and non-adherence to drug therapy. This may result in unnecessary health expenditure, directly due to redundant drug sales, and indirectly due to the increased hospitalization caused by drug-related problems. LÄS MER

  4. 19. The medical perspective in prescribing: measurements and educational strategies

    Författare :Johan Lönnbro; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prescribing quality; adverse drug reactions; clinical relevance; inter-rater reliability; education;

    Sammanfattning : Background and aims: Drug treatment is a keystone in modern healthcare and for safe prescribing of drugs, an overall medical perspective has to be applied, taking patient characteristics into account. For each medication, and all medications combined, expected benefits must be weighed against the risks of harms; adverse drug reactions, sometimes leading to hospitalization, is a matter of concern. LÄS MER

  5. 20. Safety of Medication in Paediatrics

    Författare :Kristina Star; Karin Nordin; I Ralph Edwards; Richard Irvin Cook; Uppsala universitet; []
    Nyckelord :paediatrics; adverse drug reaction; drug-related problem; medication error; patient safety; individual case safety reports; pharmacovigilance; medication; nurses; health care personnel; dosage form; NSAID; dosing; prescription; antipsychotic medicines; postmarketing surveillance; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Background: In paediatrics, the limited documentation to guide medication, the lack of suitable dosage forms, and the continuous development in childhood present a scenario where safety of medication is a particular challenge.Aim: To explore reported adverse drug reactions (ADRs) and the challenges in prescribing and administering medicines in paediatrics, in order to identify and suggest areas needing international surveillance within medication safety and improvement in the clinical setting. LÄS MER