Sökning: "Advanced Glycation End products"

Visar resultat 1 - 5 av 21 avhandlingar innehållade orden Advanced Glycation End products.

  1. 1. Glucose degradation products in patients on hemodialysis : interventional studies

    Författare :Bernd Ramsauer; Bernd Stegmayr; Henrik Hadimeri; Bengt Lindholm; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hemodialysis; advanced glycation end products; skin autofluorescence; plasma autofluorescence; glucose degradation products;

    Sammanfattning : Hemodialysis (HD) is the most frequently used treatment for end-stage renal disease. Despite all efforts to improve the outcomes, the mortality of patients on HD is still high, and this especially is related to cardiovascular diseases (CVD). LÄS MER

  3. 2. Teratogenic Predisposition in Diabetic Rat Pregnancy

    Författare :Andreas Ejdesjö; Ulf J Eriksson; Parri Wentzel; Niklas Nordquist; Gernot Desoye; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetes; malformations; teratogenic; advanced glycation end products; AGE; RAGE; oxidative stress; ROS; gene expression; Medical Cell Biology; Medicinsk cellbiologi;

    Sammanfattning : Pre-gestational diabetes increases the risk of congenital malformation in the offspring and both morbidity and mortality in the diabetic mother and her offspring. During pregnancy, high glucose levels act as a teratogen through several cellular and biochemical pathways and increased production of reactive oxygen species (ROS) has a central role in diabetic embryopathy. LÄS MER

  4. 3. Protein Damage Control during Embryonic Stem Cell Differentiation: Role of the Proteasome

    Författare :Malin Hernebring; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Embryonic Stem Cells; Proteasome; Protein Carbonylation; Advanced Glycation End products; Cell Differentiation; Oxidative stress; Aging; RNAi;

    Sammanfattning : During the lifespan of organisms ranging from yeast to humans, there is an accumulation of macromolecular damage. However, these organisms produce youthful progeny with low damage levels. This thesis focuses on how this is accomplished. LÄS MER

  5. 4. Glucose degradation products in peritoneal dialysis fluids

    Författare :Martin Erixon; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Medicine human and vertebrates ; 4-dideoxyglucosone-3-ene; 3; cytotoxicity; storage; temperature; Glucose degradation products biocompatibility; sterlization; Medicin människa och djur ; Analytical chemistry; Analytisk kemi;

    Sammanfattning : Patients suffering from renal failure must remove extracellular water and waste products from their body in order to survive. One way of doing this is by treatment with peritoneal dialysis (PD). LÄS MER

  7. 5. The inflammatory and immunogenic properties of the receptor for advanced glycation end products and its ligand, high mobility group box chromosomal protein 1

    Författare :Rille Pullerits; Göteborgs universitet; []
    Nyckelord :HMGB1; sRAGE; rheumatoid arthritis; inflammation; cytokines;

    Sammanfattning : Rheumatoid arthritis (RA) is a chronic systemic inflammatory joint disease, the pathogenesis of which is complex, involving a wide range of molecules. High mobility group box chromosomal protein 1 (HMGB1) is a nuclear protein recently recognised as a pro-inflammatory cytokine which levels are increased in RA patients. LÄS MER