Sökning: "Adult Mesenchymal Stem Cells MSCs"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden Adult Mesenchymal Stem Cells MSCs.

1. 1. Characterisation of human fetal mesenchymal stem cells

   Författare :Cecilia Götherström; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Mesenchymal stem cells; fetal stem cell transplantation; intrauterine transplantation; osteogenesis imperfecta; mixed lymphocyte culture; gene array;

   Sammanfattning : Mesenchymal stem cells (MSCs) are present in various tissues of fetal and adult origin. I isolated and expanded MSCs from human fetal 1st trimester livers and observed that they have a shorter cell doubling time compared to adult bone marrow-derived MSCs. LÄS MER

3. 2. Stem cells for cardiac regeneration

   Författare :Ivana Bulatović; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Recent studies have demonstrated a turnover of cardiomyocytes throughout the adult life. Whether this regenerative potential is due to proliferation and differentiation of resident stem cells or to the dedifferentiation of adult cardiomyocytes remains unclear. LÄS MER

4. 3. Bone marrow mesenchymal stem and progenitor cells in myeloid malignancies

   Författare :Pingnan Xiao; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Hematopoietic stem cells (HSCs) reside in bone marrow (BM) microenvironment / niche to self-renew and generate all types of mature blood cells in postnatal life. This process is called hematopoiesis. Normal hematopoiesis is tightly regulated by both intrinsic signaling in HSCs and extrinsic signals from BM niche. LÄS MER

5. 4. Extracellular factors for preservation and delivery of stromal cells

   Författare :Kim Olesen; Karl-Henrik Grinnemo; Andreas Tilevik; Wing Cheung Mak; Cecilia Österholm; Magnus Fagerlind; Yuji Teramura; Högskolan i Skövde; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Infection Biology; Infektionsbiologi;

   Sammanfattning : Modulating the immune response after a myocardial infarction seems like an appropriate strategy for reducing myocardial fibrosis. Mesenchymal Stromal Cells are immunomodulatory and have thus gained interest, but have so far not achieved the desired clinical outcomes. LÄS MER

7. 5. Development and optimization of a 3D in vitro model for osteogenic biomaterial evaluation

   Författare :Luis Oliveros Anerillas; Peyman Kelk; Paul J. Kingham; Mikko Lammi; Jöns Hilborn; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; angiogenesis; biomaterial; bone marrow mesenchymal stem cells; bone regeneration; hydrogel; osteoinduction; osteogenesis; scaffold; type I collagen; 3D culture; biology; biologi; biomedical laboratory science; biomedicinsk laboratorievetenskap; Medical Cell Biology; medicinsk cellbiologi;

   Sammanfattning : Despite the innate regenerative capabilities of bone tissue, self-repair is impaired when an injury exceeds the critical size threshold because of trauma, congenital, or pathological conditions. Autologous transplantation is the gold standard to reconstruct large bone defects. LÄS MER