Sökning: "Administration Oral"
Visar resultat 1 - 5 av 191 avhandlingar innehållade orden Administration Oral.
1. Pharmacokinetics of the enantiomers of thalidomide
Sammanfattning : Thalidomide has a chiral center and the racemate of (+)-(R) and (-)-(S)-thalidomide was introduced as a hypnotic/sedative drug in 1957. In 1961 it was withdrawn due to teratogenicity and neuropathy. There is a growing interest in thalidomide treatment of immunomodulatory diseases. LÄS MER
2. Functional Ceramics in Biomedical Applications : On the Use of Ceramics for Controlled Drug Release and Targeted Cell Stimulation
Sammanfattning : Ceramics are distinguished from metals and polymers by their inorganic nature and lack of metallic properties. They can be highly crystalline to amorphous, and their physical and chemical properties can vary widely. LÄS MER
3. Recurrent Aphthous Stomatitis - A study, with emphasis on host genetics, oral microbiota composition, and immunoregulatory networks
Sammanfattning : Recurrent aphthous stomatitis (RAS) is one of the most common oral mucosal lesions. The aetiology is unknown and currently there is no consensus regarding suitable treatment regimens. LÄS MER
4. Oral delivery of macromolecules formulated with permeation enhancers
Sammanfattning : Therapeutic macromolecules including peptides, proteins, and nucleotide-based ones (such as antisense oligonucleotides and RNAs) have great potential as drug candidates. One drawback is that they typically need to be administered parenterally via subcutaneous, intramuscular or intravenous injections. LÄS MER
5. Essays on the interaction between regulation and technology : Understanding agency and context through multiple levels of inquiry
Sammanfattning : A key challenge for implementing pioneering regulatory and technological change includes overcoming regulatory constraints and resistance from vested interest groups in favor of the status quo. This is a compilation dissertation comprising five papers and one covering paper that aims to describe and explain the interaction between agency and context under conditions of combined technological and regulatory change through multiple levels of inquiry. LÄS MER