Sökning: "Adjuvant"
Visar resultat 6 - 10 av 402 avhandlingar innehållade ordet Adjuvant.
6. Heat shock proteins as vaccine adjuvants
Sammanfattning : New efficient vaccines against infectious diseases are in demand. Some important factors impeding the vaccine development are the poor immunogenicity and the MHC restriction of the immune responses to a number of antigens. LÄS MER
7. Cell cycle alterations and 11q13 amplification in breast cancer : prediction of adjuvant treatment response
Sammanfattning : The growth and development of the breast is to a large extent regulated by oestrogens through the oestrogen receptor (ER). Activation of the ERα triggers transcription of genes that are important for cell proliferation and stimulates entry into the G1 phase of the cell cycle. LÄS MER
8. Gastrointestinal stromal tumours. On diagnosis and treatment
Sammanfattning : Gastrointestinal stromal tumours (GIST) are thought to originate from the interstitial cells of Cajal, which show many properties in common with neurons of the gastrointestinal tract. High-risk GIST has a very poor prognosis and tumour recurrence is common after intentionally curative surgery. LÄS MER
9. Experimental and population-based studies on colorectal cancer - Thymidine phosphorylase as a potential biomarker
Sammanfattning : Background: Colorectal cancer (CRC) is one of the most common malignancies, and the only reliable treatment option for cure is surgery. Method: Quantitative real-time polymerase chain reaction was used to analyze the gene expression of the enzyme thymidine phosphorylase (TP), which was related to prognostic factors (paper I, n=254), evaluated as a predictive factor (paper III, n=125), and assessed by change of treatment (paper II, n=28). LÄS MER
10. Mast cells: bad enemies or good friends? : A study of the effects of IgG immune complexes on mast cell biology
Sammanfattning : Mast cells are classically defined as bad enemies to human health due to their critical involvement in IgE-dependent allergy by virtue of the expression of the high affinity IgE receptor, FcgammaRI, on these cells. However, mouse mast cells also express FcgammaRIIB and FcgammaRIIIA, two receptors that bind IgG especially in the form of IgG immune complexes. LÄS MER