Sökning: "Adjuvant"

Visar resultat 16 - 20 av 402 avhandlingar innehållade ordet Adjuvant.

1. 16. Antibodies for better or worse or Antibody variability in an egg-laying mammal and a novel strategy in the treatment of allergies

   Författare :Jeannette Johansson; Kjell-Olov Grönvik; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Antibody; variability; platypus; allergy; vaccine; adjuvant; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; Molecular Immunology; molekylär immunologi;

   Sammanfattning : Antibodies are a central part of the immune defense system, and a large variability in their specificity is needed in order to be able to react against all possible foreign substances we may encounter during our lives. In this thesis, results are presented from investigations into how an egg-laying mammal, the Australian duck-billed platypus (Ornithorhynchus anatinus) creates antibody variability. LÄS MER

3. 17. Abdominal & pelvic radiotherapy: acute effects on inflammation, leucocytes and collagen deposition

   Författare :Louis Banka Johnson; Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rectal Neoplasms; Radiotherapy; Adjuvant; Radiation Effects; Wound Healing; Intestines - Cancer;

   Sammanfattning : [abstract missing].... LÄS MER

4. 18. More or Less IgE : Therapeutic Vaccines, Adjuvants and Genes and Their Effect on IgE Levels

   Författare :Anna Ledin; Lars Hellman; Kjell-Olov Grönvik; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; IgE; Immunoglobulin; Atopic allergy; Vaccine; Adjuvant; Dog; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

   Sammanfattning : Immunoglobulin E (IgE) is an important mediator in atopic allergies. This thesis describes the development of a therapeutic vaccine against IgE and its effects in rats and dogs. The development of an assay to determine IgE levels in dogs, and the finding of a chromosome region in rats that affects IgE levels are also reported. LÄS MER

5. 19. Starch Microparticles as an Oral Vaccine Adjuvant with Emphasis on the Differentiation of the Immune Response

   Författare :Linda Stertman; Ingvar Sjöholm; Kjell-Olov Grönvik; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; Vaccine adjuvant; Microparticles; Oral immunisation; Th1 Th2 differentiation; Mucosal immune response; Uptake; M cell; Galenisk farmaci; Pharmaceutics; Galenisk farmaci;

   Sammanfattning : Polyacryl starch microparticles have been developed as an oral vaccine adjuvant capable of inducing strong local and systemic immune responses in mice. In this thesis, the starch microparticles were studied in order to increase basic understanding of their function. LÄS MER

7. 20. Immunologic and genetic studies of rat adjuvant-induced arthritis

   Författare :Åsa Jansson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :arthritis; autoimmunity; adjuvant; incomplete Freund s adjuvant; squalene; quantitative trait locus;

   Sammanfattning : Rheumatoid arthritis (RA) is a chronic inflammatory joint disease with a multifactorial and largely unknown etiology. It is influenced by both environmental and genetic factors, and understanding of disease mechanisms and identification of disease-causing genes is hampered by the complex and polygenic nature of the disease. LÄS MER