Sökning: "Adhesive particle mixing"

Hittade 3 avhandlingar innehållade orden Adhesive particle mixing.

  1. 1. A Multi-Scale Approach To Adhesive Mixing

    Författare :Duy Nguyen; Chalmers University of Technology; []
    Nyckelord :Adhesive particle mixing; CFD simulation; multiscale; dry particle coating; regime map.; DEM simulation; dry powders for inhalation;

    Sammanfattning : Adhesive particle mixing is a fundamental process in many applications, especially in dry powders for inhalation. Despite its importance, a mechanistic process description for designing the structure of interest is still lacking. LÄS MER

  2. 2. Mechanisms of adhesive mixing for drug particle inhalation (Numerical investigation of the interplay between formulation variables)

    Författare :Mohammadreza Tamadondar; Chalmers University of Technology; []
    Nyckelord :Agglomerate; Carrier Particle; Dispersion; DPI-formulation; Adhesive mixing; Discrete Element Method;

    Sammanfattning : Formulation of therapeutic dry powders for lung drug delivery via inhalation is done via adhesive mixing. In this process, micron-sized active pharmaceutical ingredient particles are blended with relatively coarse carrier particles until stable adhesive units of carrier and drug particles are formed. LÄS MER

  3. 3. Large organic aerosols in a human exposure chamber : Applications in occupational dermatology and lung medicine

    Författare :Lennart Lundgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Aerosol; bakery dust; bronchoalveolar lavage; chamber design; dermal exposure; exposure chamber; inhalation; large organic aerosols; mannequin; neutralizer; particle size; pinewood dust; skin;

    Sammanfattning : Exposure to large organic aerosol particles may cause respiratory and skin reactions. The use of human exposure chambers offers possibilities for experimental exposure challenges carried out with patients, in research and for investigations of the effects of exposure on the skin and in the respiratory tract. LÄS MER