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Visar resultat 1 - 5 av 463 avhandlingar som matchar ovanstående sökkriterier.
1. Resilience in High Risk Work : Analysing Adaptive Performance
Sammanfattning : In today’s complexsocio-technical systems it is not possible to foresee and prepare for allfuture events. To cope with the intricacy and coupling between people,technical systems and the dynamic environment people are required tocontinuously adapt. LÄS MER
2. Optimal (Adaptive) Design and Estimation Performance in Pharmacometric Modelling
Sammanfattning : The pharmaceutical industry now recognises the importance of the newly defined discipline of pharmacometrics. Pharmacometrics uses mathematical models to describe and then predict the performance of new drugs in clinical development. LÄS MER
3. Optimal adaptive designs and adaptive randomization techniques for clinical trials
Sammanfattning : In this Ph.D. thesis, we investigate how to optimize the design of clinical trials by constructing optimal adaptive designs, and how to implement the design by adaptive randomization. LÄS MER
4. Effects of Complement Opsonization of HIV on Dendritic Cells : and Implications for the Immune Response
Sammanfattning : Dendritic cells are key players during HIV pathogenesis, and shape both the immediate immune response at the site of infection as well as directing the adaptive immune response against the virus. HIV has developed a plethora of immune evasion mechanisms that hijack dendritic cell functions, suppressing their ability to mount an accurate immune response and exploiting them for efficient viral transfer to target T cells. LÄS MER
5. Robust analysis of delaminating composites using adaptive isogeometric shell elements
Sammanfattning : Fibre reinforced composites are considered to be one of the material categories that offer the best possibilities to create efficient lightweight designs. Many companies in the transport sector therefore work towards increasing the amount of fibre composites in their products, in an attempt to lower the fuel consumption of their vehicles. LÄS MER