Sökning: "Action potential duration"

Visar resultat 16 - 20 av 22 avhandlingar innehållade orden Action potential duration.

1. 16. Electrocardiographic Imaging of Myocardial Ischemia, Infarction and Scar: Correlation with SPECT, MRI and Arrhythmias

   Författare :David G Strauss; Lund Klinisk fysiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Electrocardiography; Imaging; Arrhythmias; Ischemia; Infarction; Cardiomyopathy; SPECT; MRI;

   Sammanfattning : This thesis focuses on the development and testing of electrocardiographic (ECG) methods to diagnose and characterize myocardial ischemia, infarction and fibrosis (scar). The goal is to provide improved decision support to physicians regarding the optimal selection of patients for two costly, invasive therapies – percutaneous coronary intervention (PCI) for patients with acute myocardial infarction (MI) and implantable cardioverter defibrillators (ICDs) for patients with heart failure and reduced left ventricular ejection fraction (LVEF). LÄS MER

3. 17. Regulation of striated muscle contraction

   Författare :Ying Dou; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Background and Aims: Muscle contraction involves cross-bridge interaction between actin and myosin filaments, which is regulated by variations of intracellular [Ca2+] and influenced by several external control systems. To characterize the mechanism of contraction, we have studied the effects of pharmacological compounds influencing the actin-myosin interaction and/or Ca2+ activation systems. LÄS MER

4. 18. Exploring integrative medicine for back and neck pain : on the integration of manual and complementary therapies in Swedish primary care

   Författare :Tobias Sundberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Integrative medicine; Primary care; Complementary therapy; Manual therapy; Pragmatic; Randomised clinical trial; Cost-effectiveness; Quality-adjusted life year; SF-36;

   Sammanfattning : Background and aims: The integration of complementary therapies (CTs) with an emerging evidence base into conventional care services is common, despite limited evidence as to the clinical effectiveness of comprehensive models delivering such care, i.e. integrative medicine (IM). LÄS MER

5. 19. Physiological changes in mice deficient in different subtypes of thyroid hormone receptors : a focus on studies of heart and muscle

   Författare :Catarina Johansson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :heart rate; ECG; body temperature; [beta]-adrenergic receptor density; thyroid hormone; isometric twitch; SERCa;

   Sammanfattning : The aim of these studies was to determing the specific roles of the different subtypes of thyroid hormone receptors (TR), with focus on heart and muscle function, by using mice deficient in TR[alpha]1, TR[beta] (both TR[beta]1 and TR[beta]2 subtypes) and TR[alpha]1/[beta]. For this purpose, new techniques were set up to study various physiological parameters in these mice. LÄS MER

7. 20. Dendritic and axonal ion channels supporting neuronal integration : From pyramidal neurons to peripheral nociceptors

   Författare :Marcus Petersson; Erik Fransén; Theodore Cummins; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ion channels; computational modeling; simulations; dendrites; axons; TRP; hippocampus; C-fiber nociceptors; pain;

   Sammanfattning : The nervous system, including the brain, is a complex network with billions of complex neurons. Ion channels mediate the electrical signals that neurons use to integrate input and produce appropriate output, and could thus be thought of as key instruments in the neuronal orchestra. LÄS MER