Sökning: "Acetate Kinase."

Visar resultat 21 - 23 av 23 avhandlingar innehållade orden Acetate Kinase..

  1. 21. Platelet function in polycythemia vera : studies of agonist and cytokine induced platelet activation

    Författare :Katarina Le Blanc; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Polycythemia vera (PV) is a malignant myeloproliferative disorder characterized by an increased red cell mass and most often accompanied by leukocytosis and thrombocytosis. The pathogenic mechanisms behind PV are still largely unknown. LÄS MER

  2. 22. Immunomodulation by intravenous immunoglobulin : the effect on cytokine production studied at the single-cell level

    Författare :Ulrika Skansén-Saphir; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Preparations of pooled human immunoglobulin for intravenous use (IVIg) have an established therapeutic role in immunodeficiencies, Idiopathic Thrombocytopenic Purpura and Kawasaki's disease and has been attempted in other immunologically mediated conditions including autoimmunity, malignancies, bone marrow transplantation and serious infections such as group A streptococcal toxic shock syndrome. The effects of IVIg on cytokine synthesis in peripheral blood mononuclear cells (PBMC) was studied in vitro by applying a new immunohistochemical method for detection of cytokine production at a single cell level. LÄS MER

  3. 23. The Lysosomal-Mitochondrial Axis Theory of Apoptosis

    Författare :Ming Zhao; Sten Orrenius; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : In many cases, apoptosis may be initiated by a minor lysosomal destabilization, which some time later is followed by a secondary, more pronounced, lysosomal rupture. After exposure to low concentrations of sphingosine, a lysosomotropic detergent, Jurkat and J774 cells underwenr apoptotic cell death, while cells exposed to higher concentrations of this agent showed necrosis. LÄS MER