Sökning: "Abdominal sepsis"

Visar resultat 1 - 5 av 26 avhandlingar innehållade orden Abdominal sepsis.

1. 1. Severe sepsis : epidemiology and sex-related differences in inflammatory markers

   Författare :Sofie Jacobson; Ola Winsö; Stefan Söderberg; Peter Larsson; Else Tönnesen; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Severe sepsis; Leptin; Adiponectin; Mannose-binding lectin; Sex; anestesiologi; Anaesthesiology;

   Sammanfattning : Background.  Sepsis is a syndrome associated with high mortality rates, substantial morbidity and high costs of care. The incidents of sepsis is reported to be high and controversy exists whether gender affect severity or outcome. LÄS MER

3. 2. Adhesive and signaling mechanisms in abdominal sepsis

   Författare :Su Zhang; Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; abdominal sepsis; lung; infection; neutrophil; chemokines; T-cells; HMG-CoA reductase; NFAT;

   Sammanfattning : Sepsis is a major cause of mortality in intensive care units despite decades of scientific efforts. The lung is recognized as the most sensitive and critical organ affected by the hyper-inflammatory response in septic patients. Immune cell dysfunction develops in later phases of sepsis making patients susceptible to infections. LÄS MER

4. 3. Rac1 signaling regulates platelet-dependent inflammation abdominal sepsis

   Författare :Rundk Hwaiz; Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; abdominal sepsis; Rac1; platelet; neutrophil; chemokine; inflammation;

   Sammanfattning : Sepsis is a systemic inflammatory response syndrome to a localized or systemic infection that leads to the over production of proinflammatory cytokines and the ultimate failure of multiple organ systems. However, little is known about the potential role of Rac1 in controlling sepsis-induced intracellular signaling pathways. LÄS MER

5. 4. Platelet-dependent pulmonary recruitment of neutrophils in abdominal sepsis

   Författare :Milladur Rahman; Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; abdominal sepsis; neutrophil recruitment; platelet; lung injury;

   Sammanfattning : Sepsis and subsequent multiple organ failure remain the major cause of mortality in intensive care units. Leukocyte-mediated tissue damage is a key feature in septic lung injury. Accumulating data suggest that platelets play a role in inflammation and tissue injury. LÄS MER

7. 5. Neutrophil and endothelial cell-mediated inflammation in abdominal sepsis

   Författare :Zhiyi Ding; Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sepsis; lung; neutrophil; endothelial cell; neutrophil extracellular traps; inflammation; capillary; post capillary venules; cytoskeleton; RNAseq;

   Sammanfattning : Sepsis is defined as a life-threatening condition caused by a dysregulated host response to infection. Neutrophils are themost abundant innate immune cells of the body and play a key role in septic pathogenesis. LÄS MER