Sökning: "ATP-dependent chromatin remodeling"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden ATP-dependent chromatin remodeling.

  1. 1. Chromatin Remodeling by BRG1 and SNF2H : Biochemistry and Function

    Författare :Patrik Asp; Ann-Kristin Östlund Farrants; Anthony Imbalzano; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; chromatin; chromatin remodeling; SWI SNF; ISWI; BRG1; SNF2H; Prp8; RNA; transcription; Cell and molecular biology; Cell- och molekylärbiologi;

    Sammanfattning : Chromatin is a highly dynamic, regulatory component in the process of transcription, repair, recombination and replication. The BRG1 and SNF2H proteins are ATP-dependent chromatin remodeling proteins that modulate chromatin structure to regulate DNA accessibility for DNA-binding proteins involved in these processes. LÄS MER

  3. 2. Allosteric control of ALC1-catalyzed nucleosome remodeling

    Författare :Laura C. Lehmann; Sebastian Deindl; Stefan D. Knight; Felix Müller-Planitz; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ALC1; CHD1L; ATP-dependent chromatin remodeling; nucleosome; allosteric regulation; autoinhibition; macro domain; PARP; ADP-ribosylation; DNA damage; acidic patch; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi;

    Sammanfattning : The genetic information of eukaryotic cells is packaged inside the nucleus as chromatin. This packaging restricts access to the DNA and therefore represents a barrier for processes such as DNA replication, repair, and gene expression. LÄS MER

  4. 3. Chromatin remodelers and their roles in chromatin organization

    Författare :Annelie Strålfors; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The DNA in the eukaryotic nucleus is organized into a complex DNA-protein structure called chromatin. The basic repeating unit of chromatin is the nucleosome, which consists of 147 bp of DNA wrapped around a histone protein octamer. LÄS MER

  5. 4. The CHD chromatin remodeling factors in schizosaccharomyces pombe

    Författare :Julian Walfridsson; Karl Ekwall; Pernilla Bjerling; Stefan Björklund; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Regulation of chromatin structure is essential in a wide variety of processes including transcriptional regulation, recombination, replication, chromosome segregation, development and differentiation. The enzymes that are central in regulating chromatin structure can be classified into two major groups. LÄS MER

  7. 5. Chromatin remodeling and dna topology in transcription and genome stability

    Författare :Jenna Persson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Eukaryotic DNA is wrapped around histone proteins to form nucleosomes, the fundamental repeating unit of chromatin. DNA packaging into chromatin both solves and creates problems. It allows the centimeters, or even meters, of DNA that constitute a eukaryotic genome to fit inside a micrometer-scale cell nucleus. LÄS MER