Sökning: "ATM"
Visar resultat 16 - 20 av 91 avhandlingar innehållade ordet ATM.
16. Repair of DNA double-stranded breaks in human cells
Sammanfattning : DNA is continuously subjected to degradation. Therefore, our cells need to constantly repair its DNA to prevent mutations and in the long run cancer. In mammalian cells, when DNA is broken right off, a double-stranded break (DSB) is produced, and the ends are ligated by a process called non-homologous end-joining (NHEJ). LÄS MER
17. Molecular studies in breast cancer susceptibility genes
Sammanfattning : Breast cancer is the most common malignancy among women, with a cumulative risk of approximately 12% by the age of 85. Of the breast cancer cases, 5-10% are hereditary. LÄS MER
18. Functional analysis of genetic variants in putative low penetrate breast cancer genes
Sammanfattning : Paper I & II: CDH1 germline mutations predispose individuals to diffuse gastric cancer, but its role in breast cancer is less clear. Somatic CDH1 mutations were reported to be frequent in lobular tumours (ILC), but they have not been found in ductal carcinomas (IDC). LÄS MER
19. A genetic study on familial breast cancer predisposing genes
Sammanfattning : Breast cancer is the most common malignant disease among women in the western world and 10% of all breast cancer is assumed to constitute hereditary cases. Two major genes, BRCA1 and BRCA2, can only explain a fraction of familial breast cancer. The ATM carriers have high risk of developing breast cancer. LÄS MER
20. Low Power Techniques for Fast CMOS Buffer Memories
Sammanfattning : The thesis deals with circuit-level aspects of CMOS buffer SRAMs where the data throughput rate is a more important metric than access time or storage capacity. One aspect is the increased write cycle related power consumption that is the consequence of a high write ratio combined with a long word-length. LÄS MER