Sökning: "AT4"

Hittade 2 avhandlingar innehållade ordet AT4.

  1. 1. Design and Synthesis of Angiotensin IV Peptidomimetics Targeting the Insulin-Regulated Aminopeptidase (IRAP)

    Författare :Hanna Andersson; Anders Hallberg; Anders Karlén; Federico Corelli; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiotensin IV; AT4; insulin-regulated aminopeptidase IRAP ; inhibitor; peptidomimetics; γ-turn mimetic; macrocycle; Pharmaceutical chemistry; Läkemedelskemi; Medicinal Chemistry; Läkemedelskemi;

    Sammanfattning : Peptidomimetics derived from the bioactive hexapeptide angiotensin IV (Ang IV, Val1-Tyr2-Ile3-His4-Pro5-Phe6) have been designed and synthesized. These peptidomimetics are aimed at inhibiting the insulin-regulated amino peptidase (IRAP), also known as the AT4 receptor. LÄS MER

  3. 2. Fabrication and Characterization of Aluminum Single Electron Transistors for Scanning Probes

    Författare :Henrik Brenning; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; radio frequency single electron transistor; scanning probe; charging energy; nano fabrication; noise; scanning SET; SET; cantilever; AFM; RC-product; micro mechanics;

    Sammanfattning : The main objective of the work presented in this thesis was to fabricatescanning single electron transistor probes that operate at pumped liquid heliumtemperatures. This required single electron transistors (SETs) with low resistance (R_) and relatively high charging energy (E_C), and the technology tointegrate SETs onto probes. LÄS MER