Sökning: "AT1"

Visar resultat 6 - 10 av 41 avhandlingar innehållade ordet AT1.

1. 6. Vascular Endothelin and Angiotensin Receptors Regulation in Inflammatory Arterial Disorders

   Författare :Ivan Dimitrijevic; Lund Medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ischemic heart disease; resistance artery; giant cell arteritis; temporal artery; immunohistochemistry; AT2 receptor; AT1 receptor; Endothelin-1; ETA receptor; ETB receptor;

   Sammanfattning : The present thesis is aimed to examine the hypothesis that the degree of vascular inflammation correlates with the expression of vascular endothelin and angiotensin receptors. The receptor changes were studied in subcutaneous resistance arteries in patients with different degrees of ischemic heart disease (IHD). LÄS MER

3. 7. Angiotensin II and vascular disease. Studies in rats and atherosclerosis-prone mice

   Författare :Maria E Johansson; Göteborgs universitet; []
   Nyckelord :angiotensin II; atherosclerosis; AT1 receptor; AT2 receptor; blood pressure; hyperinsulinemia; hypertension; oxidative stress; salt; vascular disease; vascular function;

   Sammanfattning : Angiotensin II (Ang II) is of importance for a number of physiological processes but also plays an important pathophysiological role in cardiovascular disease. The aim of this thesis was to evaluate the role of Ang II in hypertension-related atherosclerosis and vascular disease and to investigate possible anti-atherosclerotic effects of the angiotensin II, type 2 (AT2) receptor. LÄS MER

4. 8. The Nitric Oxide and Renin-angiotensin II Systems in the Human Esophagus

   Författare :Anna Casselbrant; Göteborgs universitet; []
   Nyckelord :Acid; nitric oxide; nitric oxide synthase; salivary secretion; renin-angiotensin; At1 receptor; AT2 receptor; mucosa; smooth muscle; contractility; peristaltic; high-pressure zone;

   Sammanfattning : .... LÄS MER

5. 9. Design and Synthesis of 11C-Labelled Compound Libraries for the Molecular Imaging of EGFr, VEGFr-2, AT1 and AT2 Receptors : Transition-Metal Mediated Carbonylations Using [11C]Carbon Monoxide

   Författare :Ola Åberg; Bengt Långström; Nicholas Long; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; [11C]carbon monoxide; isotopic labelling; PET; acrylamide; EGFR; VEGFR-2; 11C; Organic chemistry; Organisk kemi; Organic Chemistry; Organisk kemi; Organic Pharmaceutical Chemistry; Organisk farmaceutisk kemi;

   Sammanfattning : This work deals with radiochemistry and new approaches to develop novel PET tracers labelled with the radionuclide 11C.Two methods for the synthesis of 11C-labelled acrylamides have been explored. LÄS MER

7. 10. Effects of the angiotensin II type 1 receptor blocker (AT₁ receptor blocker) candesartan cilexetil on systemic and renal haemodynamics in hypertensive patients

   Författare :Katarina Fridman; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Established primary hypertension is primarily characterised by elevated peripheral resistance and an increase in renal vascular resistance. Antagonism of angiotensin II may be a particularly relevant intervention in this condition, as angiotensin II is known to act both as a powerful vasoconstrictor and as a stimulus to vascular hyperthrophy. LÄS MER