Sökning: "ASCUS"

Visar resultat 1 - 5 av 9 avhandlingar innehållade ordet ASCUS.

  1. 1. Human papillomaviruses of skin and genital lesions

    Författare :Hanna K Johansson; Malmö Klinisk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human papillomavirus; condylomas; ASCUS; CIN1; non-melanoma skin cancer; metagenomic sequencing; PCR;

    Sammanfattning : Around 5% of all cancer cases worldwide are caused by human papillomavirus (HPV) which has been established as the cause of cervical cancer and genital warts (condylomas). Cutaneous HPV types have been weakly associated with non-melanoma skin lesions such as squamous cell carcinoma (SCC) and actinic keratosis (AK). LÄS MER

  2. 2. Anatomy and taxonomy of cetrarioid lichens

    Författare :Arne Thell; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; taxonomi; chemotaxonomy. Physiology of nonvascular plants; phytogeography; morphology; taxonomy; Systematic botany; pycnoconidia; ascus structures; anatomy; Systematisk botanik; cetrarioid lichens; Ascomycotina; Parmeliaceae; morfologi; kemotaxonomi. Växters fysiologi inte kärlväxter .;

    Sammanfattning : The anatomy of the cetrarioid lichens (Parmeliaceae) has been studied, and the taxonomy revised. Special attention has been paid to reproductive structures, in particular the asci and pycnoconidia. Two types of asci are recognized. The Cetraria type is narrowly clavate, bears an amyloid ring structure in the tholus, and has a small axial body. LÄS MER

  3. 3. Prevention of cervical cancer through use of liquid-based cytology and supplementary HPV testing in population-based screening

    Författare :Maria Fröberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The aim of this project is to evaluate an alternative screening strategy using liquid- based cytology (LBC), and supplementary detection of human papillomavirus (HPV) in cases of minor cytological abnormalities (atypical squamous cells of undetermined significance, ASCUS, and low-grade squamous intraepithelial lesion, LSIL). Within population-based screening in Stockholm, Sweden, we alternated screening using LBC with supplementary HPV testing in ASCUS and LSIL (LBC+HPV testing, using Linear Array HPV genotyping Assay, Roche diagnostics) and conventional cytology (CC), from September 2005 to December 2006. LÄS MER

  4. 4. HPV genotyping and potential progression markers in cervical intraepithelial neoplasia : clinical and diagnostic impact

    Författare :Sophia Brismar Wendel; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The aim of this thesis is to identify clinically useful early molecular markers to predict progression to carcinoma in women with preinvasive lesions of the cervix, for the purpose of improving care of these women and enabling more individualized treatment. In order to define the human papillomavirus (HPV) types in minor cytological abnormalities, 343 liquid-based cytology (LBC) samples with atypical squamous cells of uncertain significance (ASCUS) and with low-grade squamous intraepithelial lesions (LSIL) were genotyped using Linear Array. LÄS MER

  5. 5. Human papillomavirus testing and its application in cervical cancer prevention

    Författare :Anna Söderlund Strand; Malmö Klinisk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : SUMMARY Because of the strong causal relationship between persistent infections of human papillomavirus (HPV) and cervical intraepithelial neoplasia (CIN) and cancer, HPVtesting has been proposed for improvement of cervical screening programs, including triaging and follow-up after treatment for CIN. We developed two new methods for HPV-testing with genotyping: A high-throughput HPV genotyping method that uses mass spectrometry for detection of the products of type-specific mass extend reactions, and a method with particularly sensitive detection of a broad spectrum of HPV-types, also in the case of multiple infections, that uses type-specific probes coupled to fluorescent beads for detection on the Luminex platform. LÄS MER