Sökning: "ART Outcomes"

Visar resultat 11 - 15 av 82 avhandlingar innehållade orden ART Outcomes.

  1. 11. Paediatric HIV infection in Maputo, Mozambique : horizontal transmission, treatment outcomes and drug resistance

    Författare :Paula Vaz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This thesis describes observational studies performed at the main reference centre for paediatric HIV care and management in Mozambique, which is one of the countries most strongly affected by the AIDS pandemic. These studies focused on horizontal transmission, treatment outcomes and paediatric antiretroviral drug resistance in a cohort of HIV-1-infected children. LÄS MER

  3. 12. The HIV-1 epidemic in Ethiopia – transmission patterns, antiretroviral drug resistance and treatment outcomes

    Författare :Dawit Assefa; Malmö Klinisk virologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; HIV drug resistance HIVDR ; Phylodynamics; Phylogenetic; Molecular epidemology; transmitted HIVDR; acquired HIVDR; pre-treatment HIVDR; Integrase strand transfer inhibitors INSTI ; Ethiopia; antiretroviral therapy;

    Sammanfattning : A comprehensive understanding of local HIV epidemiology is essential for monitoring transmission, designing, implementing, and evaluating HIV intervention strategies. In paper I, we used a total of 1276 HIV-1 subtype C pol sequences and employed state-of-art phylogenetic and phylodynamic tools to describe the molecular epidemiology of HIV in Ethiopia. LÄS MER

  4. 13. Improving treatment outcomes for patients with pulmonary tuberculosis in Tanzania : host and pathogen factors

    Författare :Tumaini Joseph Nagu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Tuberculosis (TB) causes more than 1.2 million deaths each year globally. Yet, survivors of tuberculosis are left with long term sequelae of chronic inflammatory responses with consequent reduced quality of life. LÄS MER

  5. 14. Immunological and virologica response to antiretroviral treatment (art) in patients infected with different HIV-1 genetic subtypes

    Författare :Ann Atlas; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV- 1 genetic subtype; CD4 T cell count; viral load; activation markers; IL-7;

    Sammanfattning : Genetic analyses of different strains of HIV- 1 have shown that isolates can be subdivided into groups, subtypes and circulating recombinant forms. Nine different genetic HIV-1 subtypes have been identified so far, named as A, B, C, D, F, G, H, J and K. LÄS MER

  7. 15. Antiretroviral drug resistance and treatment outcomes of human immunodeficiency virus type-1 : implications for low and middle income countries

    Författare :Amanda Häggblom; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : My thesis contains comprehensive studies of antiretroviral treatment (ART) naïve and experienced patients from the beginning of the Swedish HIV-1 epidemic. Paper I was the first study to describe the ART usage and occurrence acquired drug resistance mutations (DRM) at a population level in Sweden over time and we used data derived between 1997-2011. LÄS MER