Sökning: "APOE"

Visar resultat 6 - 10 av 165 avhandlingar innehållade ordet APOE.

  1. 6. Olfactory Function : The Influence of Demographic, Cognitive, and Genetic Factors

    Författare :Margareta Hedner; Maria Larsson; Lars-Göran Nilsson; Claire Murphy; Stockholms universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Olfaction; odor identification; odor threshold; odor discrimination; aging; gender; ApoE; BDNF; val66met; association study; population-based; Psychology; psykologi;

    Sammanfattning : Olfactory function is affected by demographic, cognitive, and genetic factors. In the present thesis, three empirical studies investigated individual differences in olfactory ability. Study I explored demographic and cognitive correlates in common olfactory tasks; odor detection, odor discrimination, and odor identification. LÄS MER

  3. 7. Mathematical aspects of apolipoprotein kinetics, with focus on metabolic diseases

    Författare :Valentina Fermanelli; Chalmers tekniska högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; apoA4; apolipoproteins; abdominal obesit; type II diabetes; NLMEM; apoC-III; mathematical modelling; apoE;

    Sammanfattning : Biomathematics is a branch of science that aims at describing biological processes in mathematical terms to frame and solve otherwise unsolvable research questions in the biological and medical field. Cardiovascular diseases are the number one cause of death in the world. LÄS MER

  4. 8. Genetic Studies of Alzheimer's Disease

    Författare :Elin Blom; Anna Glaser; Martin Ingelsson; Lars Lannfelt; Jan Hillert; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; Linkage; Affected sib-pairs; APOE; APP duplication; 10q21; 19q13; Wnt signaling; Geriatrics and medical gerontology; Geriatrik och medicinsk gerontologi;

    Sammanfattning : Patients with Alzheimer's disease (AD) often have a family history of the disease, implicating genetics as a major risk factor. Three genes are currently known to cause familial early-onset AD (65 years), only the APOE gene has repeatedly been associated to AD, where the ε4 allele increases disease risk and decreases age at onset. LÄS MER

  5. 9. Coffee and gene interaction. The effect on methionine and lipid metabolism

    Författare :Elisabeth Strandhagen; Göteborgs universitet; []
    Nyckelord :coffee; homocysteine; cholesterol; folate; pyridoxine; MTHFR; APOE; gene; polymorphism; interaction;

    Sammanfattning : Background: Different dietary factors influence the risk of coronary heart disease (CHD), most likely in an interaction with genetic polymorphisms. The knowledge about such interactions is insufficient. Some observational studies have shown an association between coffee and CHD, others have not. Coffee consumption affects some CHD risk factors, e. LÄS MER

  7. 10. Air pollution and dementia in a low exposure setting : the role of noise, olfaction, and theapoe gene

    Författare :John Andersson; Maria Nordin; Anna Oudin; Anna Sundström; Tom Russ; Umeå universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Air pollution; Road traffic; NOx; dementia; APOE; Alzheimer’s disease; Apolipoprotein E; olfaction; particulate matter; vascular dementia; odor identification; odor detection; Psychology; psykologi;

    Sammanfattning : Previous research indicates an association between air pollution exposure, and risk of dementia. Still, a number of factors that may play a role in this association remain to be explored. LÄS MER