Sökning: "APOC1"

Hittade 2 avhandlingar innehållade ordet APOC1.

  1. 1. Endogenous and exogenous factors affecting lipoprotein lipase activity

    Författare :Mikael Larsson; Gunilla Olivecrona; Aivar Lookene; Ira Tabas; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LPL; APOC1; APOC2; APOC3; ANGPTL4; enzyme inactivation; lipoprotein metabolism; triglycerides; fatty acids; hypertriglyceridemia; CVD; small molecule screening; structure-activity relationship; cardiovascular disease; hjärt- och kärlforskning;

    Sammanfattning : Individuals with high levels of plasma triglycerides are at high risk to develop cardiovascular disease (CVD), currently one of the major causes of death worldwide. Recent epidemiological studies show that loss-of-function mutations in the APOC3 gene lower plasma triglyceride levels and reduce the incidence of coronary artery disease. LÄS MER

  3. 2. Living longer than expected : protective and risk factors related to human longevity

    Författare :Debora Rizzuto; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Mortality;

    Sammanfattning : The scientific community has become increasingly interested in understanding what lies behind the continuing extension of the human lifespan. The main aim of this thesis was to better understand the association between health status, lifestyle, genetic factors and survival in advanced age. LÄS MER