Sökning: "APOA1"

Visar resultat 1 - 5 av 14 avhandlingar innehållade ordet APOA1.

  1. 1. Studies on effects of antioxidants on arterial thrombosis and endothelial cell injury : With special reference to Tocopherols and ApoA1 Milano

    Författare :Dayuan Li; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; tocopherols; apoA1 Milano; platelet aggregation; thrombosis; superoxide dismutase; nitric oxide synthase; endothelial cells; oxidized LDL; transcription factor; apoptosis; Kirurgi; Surgery; Kirurgi; rättsmedicin; Forensic Medicine;

    Sammanfattning : Coronary arterial endothelial injury and thrombosis are believed to be critical factors in the pathogenesis of coronary artery disease (CAD). Experimental studies have provided evidence for au inverse relation between acute coronary events and antioxidant intake. LÄS MER

  3. 2. Gene and Protein Profiling of the Preeclamptic Placenta

    Författare :Magnus Centlow; Lund Obstetrik och gynekologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antigen presentation; APOA1; hemoglobin; immunohistochemistry; in situ hybridization; Microarray; 2D-PAGE; uterine artery bilateral notching;

    Sammanfattning : Aims State-of-the-art methodology was used to screen and profile the placenta, gene and protein expression, for changes related to preeclampsia (PE) and cases with increased resistance in the uterine arteries. Women with increased resistance in the uterine arteries have increased risk of developing PE. LÄS MER

  4. 3. Studies on lipoprotein metabolism and atherogenesis

    Författare :Katharina Slätis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :ApoA1; ApoB; ApoE; atherosclerosis; bile acids; cholic acid; cholesterol; cholesterol absorption; CYP7A1; CYP8B1; dexamethasone; GC-1; PAI-1; thyroid hormone receptor; very low density lipoprotein receptor;

    Sammanfattning : Atherosclerosis is the primary cause of cardiovascular events such as angina pectoris and myocardial infarction, which together with stroke are responsible for around 50% of all deaths in the United States and Europe. Usually atherosclerosis develops over several decades and leads to a progressive narrowing of arterial vessels. LÄS MER

  5. 4. Structural studies of HDL and applications of EM on membrane proteins

    Författare :Lin Zhu; Hans Hebert; Caroline Jegerschöld; Catherine Vénien-Bryan; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; high density lipoprotein; rHDL; apoA-I; transmission electron microscopy; membrane protein; nanodisc; Salipro; transporter; Technology and Health; Teknik och hälsa;

    Sammanfattning : A large number of proteins interact with biological membranes, either integrated in the membrane (PepTSo2), embedded on a membrane surface (5-lipoxygenase) or encircling a cutout of lipid bilayer (apolipoprotein1 (apoA-I). They function as transporters, receptors or biocatalysts in cellular processes like inflammation or cholesterol transport which are touched upon here. LÄS MER

  7. 5. Implications of Heparan Sulfate and Heparanase in Inflammatory Diseases

    Författare :Andreas Digre; Jin-Ping Li; Lena Kjellén; Liliana Schaefer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heparanase; Heparan sulfate; Inflammation; Inflammatory diseases; Autoimmune diseases; Amyloidosis; Reumathoid arthritis; SAA; APP; A beta; Neuroinflammation; Medical Science; Medicinsk vetenskap; Medical Biochemistry; Medicinsk biokemi; Immunologi; Immunology; Neurology; Neurologi;

    Sammanfattning : Heparan sulfate (HS), an unbranched sulfated carbohydrate chain, and the HS-degrading enzyme heparanase play important roles in physiological and pathological processes during all stages of life, from early embryogenesis to ageing. Accumulated information shows that HS and heparanase are involved in inflammatory processes and associated diseases, e. LÄS MER