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Visar resultat 1 - 5 av 8 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Clincal Aspects of Biological Brain Damage Markers

   Författare :Johan Undén; Neurokirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomarkers markers; traumatologi; Neurology; Kirurgi; ortopedi; orthopaedics; traumatology; Surgery; intensivvård; Anestesiologi; intensive care; hematoma haematoma; Anaesthesiology; epidural; extracerebral; neurointensive care; head injury; stroke; APC APC-PCI; GFAP; NSE; S100 S-100 S100B S100BB; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; brain damage injury; serum;

   Sammanfattning : Biomarkers for organ damage and/or dysfuntion are used in almost all areas of medicine. The brain has eluded this technological development for some time. Recently, the S100B protein has been shown to be a promising marker of brain damage. However, before S100S can reach clinical reality, several problems must be solved. LÄS MER

3. 2. Circulating biomarkers in patients with abdominal aortic aneurysm

   Författare :Despina Flondell-Sité; Vaskulära sjukdomar - kliniska studier; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; matrix metalloproteinases; biomarkers; risk factors; fibrinolysis; coagulation; inflammation; Abdominal aortic aneurysm; statin; interleukin 6.; APC-PCI complex; serpine-1; endothelin-1;

   Sammanfattning : Abdominal aortic aneurysm (AAA) develops in 3-6% of the population over 65 years and affects mainly men. AAA has a complex etiology involving inflammation, proteolysis, fibrinolysis and coagulation. LÄS MER

4. 3. Clinical probability assessment and biochemical markers in the diagnosis of deep vein thrombosis

   Författare :Johan Elf; Malmö Klinisk koagulationsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Venous thrombosis; APC-PCI complex.; D-Dimer; Clinical probability; Diagnosis;

   Sammanfattning : The combination of pre-test clinical probability assessment and D-dimer test is now widely applied in the diagnostic process of DVT. The general objective of the present investigation was to validate these results in a Swedish routine emergency setting were the prevalence of the disease is high and were the clinical probability assessment was handled by many junior physicians. LÄS MER

5. 4. Coagulation disturbances in the critically ill patient with special reference to prediction of outcome

   Författare :Gunnar Nilsson; Anestesiologi och intensivvård; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; protein C; mortality; intensive care; health economics; global haemostatic tests; blood coagulation disorders; APC-PCI complex; abdominal aortic aneurysm operation; antithrombin; Medicin människa och djur ;

   Sammanfattning : Critically ill patients in intensive care units (ICU) often have coagulation disturbances. Clinical manifestations such as thromboembolism and/or bleeding may result from activation and consumption of coagulation factors and inhibitors. Disseminated intravascular coagulation (DIC) is a severe condition with an often-poor prognosis. LÄS MER

7. 5. Development of Methods for Measuring Protein C Inhibitor and Antithrombin: Use of Monoclonal Antibodies against the Reactive Center Loop-Inserted Forms of the Serpins

   Författare :Margareta Kjellberg; Malmö Klinisk kemi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; monoclonal antibody; latent antithrombin; immunoassay; cleaved PCI; cleaved antithrombin; Antithrombin; APC-PCI complex;

   Sammanfattning : Protein C inhibitor (PCI) and antithrombin (AT) are serine protease inhibitors (serpins) that are involved in the regulation of coagulation. Like other inhibitory serpins, PCI and AT adopt different structural conformations that are related to their functions. LÄS MER