Sökning: "AMP"

Visar resultat 11 - 15 av 163 avhandlingar innehållade ordet AMP.

1. 11. Modulation of serous salivary gland function by the sympathetic nervous system : a biochemical and ultrastructural study with special reference to β-adrenoceptor subtypes

   Författare :Roger Henriksson; Umeå universitet; []
   Nyckelord :Rat parotid gland; guinea-pig submandibular gland; ß-adrenoceptor subtypes; sympathetic denervation; sympathetic superstimulation; amylase secretion; cyclic AMP; ultrastructural stereology;

   Sammanfattning : The aim of the present investigation was to study the influence of the sympathetic nervous system and of various adrenoceptor agents on enzyme secretion and morphology in rat parotid and guinea-pig submandibular glands. Biochemical methods were combined with electron microscopical techniques. LÄS MER

3. 12. Transport and release of insulin granules during biphasic insulin secretion

   Författare :Rosita Ivarsson; Diabetes - öpatofysiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; Physiology; granule transport; Myosin 5a; Cyclic AMP; NADPH; Motor protein; Insulin secretion; Cytoskeleton;

   Sammanfattning : Glucose-evoked insulin secretion exhibits two phases: The first phase represents exocytosis of insulin granules situated at the plasma membrane, whereas the second phase reflects insulin release from granules continuously recruited to the plasma membrane. This thesis investigates different aspects of phasic insulin secretion, with the specific aims to elucidate the possible contribution of insulin granule transport, as well as to study the influence of the nucleotides cAMP and NADPH to this process. LÄS MER

4. 13. AMP-activated protein kinase : the connection between exercise and type II diabetes

   Författare :Brian R Barnes; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Skeletal muscle; glucose transport; AMP-activated protein kinase; AMPK gamma 3 exercise; Type 2 diabetes; insulin resistance; metabolism;

   Sammanfattning : Skeletal muscle insulin resistance is a hallmark feature of Type 2 diabetes. Physical exercise/muscle contraction elicits an insulin-independent increase in glucose transport and perturbation of this pathway can bypass defective insulin signaling. LÄS MER

5. 14. Skeletal muscle metabolic flexibility : the roles of AMP-activated protein kinase and calcineurin

   Författare :Yun Chau Long; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Skeletal muscle; metabolism; glucose; lipid; gene expression; AMP-activated protein kinase; calcineurin; exercise;

   Sammanfattning : Skeletal muscle fibers differ considerably in their metabolic and physiological properties. The metabolic properties of skeletal muscle display a high degree of flexibility which adapts to various physiological demands by shifting energy substrate metabolism. LÄS MER

7. 15. Studies on intracellular phosphoproteins : the cyclic 3',5'-amp-dependent phosphorylation of pyruvate kinase (type L)

   Författare :Olle Ljungström; Uppsala universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : .... LÄS MER