Sökning: "AMP-activated protein kinase"

Visar resultat 1 - 5 av 20 avhandlingar innehållade orden AMP-activated protein kinase.

  1. 1. AMP-activated protein kinase : The connection between exercise and type II diabetes

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Physiology and Pharmacology

    Författare :Brian R Barnes; Karolinska Institutet.; Karolinska Institutet.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skeletal muscle; glucose transport; AMP-activated protein kinase; AMPK gamma 3 exercise; Type 2 diabetes; insulin resistance; metabolism;

    Sammanfattning : Skeletal muscle insulin resistance is a hallmark feature of Type 2 diabetes. Physical exercise/muscle contraction elicits an insulin-independent increase in glucose transport and perturbation of this pathway can bypass defective insulin signaling. LÄS MER

  2. 2. Skeletal muscle metabolic flexibility : The roles of AMP-activated protein kinase and calcineurin

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Molecular Medicine and Surgery

    Författare :Yun Chau Long; Karolinska Institutet.; Karolinska Institutet.; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skeletal muscle; metabolism; glucose; lipid; gene expression; AMP-activated protein kinase; calcineurin; exercise;

    Sammanfattning : Skeletal muscle fibers differ considerably in their metabolic and physiological properties. The metabolic properties of skeletal muscle display a high degree of flexibility which adapts to various physiological demands by shifting energy substrate metabolism. LÄS MER

  3. 3. LKB1 signaling pathways in adipocytes - Focus on the AMPK-related kinase SIK2

    Detta är en avhandling från Department of Experimental Medical Science, Lund Univeristy

    Författare :Emma Henriksson; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2012]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipocytes; signal transduction; protein phosphorylation; LKB1; SIK2; SIK3; cAMP;

    Sammanfattning : Adipose tissue does not only store and release energy in response to hormones, it is also known as an endocrine organ, secreting important factors and hormones that influence for example appetite and insulin sensitivity. The association of type 2 diabetes with obesity has been known for quite some time. LÄS MER

  4. 4. Protein kinases in hormonal regulation of adipocyte metabolism

    Detta är en avhandling från Protein Phosphorylation, Faculty of Medicine

    Författare :Christine Berggreen; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adipocyte; PKB; AMPK; SIK3; insulin; catecholamines; lipolysis; lipogenesis; glucose uptake; de novo fatty acid synthesis; A769662; Akti; cAMP;

    Sammanfattning : Abstract Along with liver and muscle tissue, adipose tissue helps maintain normal levels of glucose and lipids in the blood and has a very important role when it comes to storing lipids that can provide whole-body energy. After a meal is ingested, adipocytes take up glucose from the circulation and use it as a substrate for synthesis of new fatty acids (FAs) in a process known as de novo fatty acid synthesis, as well as for synthesis of glycerol. LÄS MER

  5. 5. Salt-inducible kinases in adipose tissue

    Detta är en avhandling från Lund University, Faculty of Medicine

    Författare :Johanna Sernevi Säll; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; salt-inducible kinase; SIK; SIK2; fettväv; fettceller; insulinsignalering; glukosupptag; fetma; insulinresistens; salt-inducible kinase; SIK; SIK2; adipose tissue; adipocytes; insulin signalling; glucose uptake; obesity; insulin resistance;

    Sammanfattning : Fetma och typ 2 diabetes är stora folksjukdomar som ökar i rasande takt världen över. En gemensam nämnare för dessa sjukdomar är att de vävnader i kroppen som reglerar ämnesomsättningen, t.ex. fettvävnaden, förlorar känsligheten för hormonet insulin så att det inte längre fungerar normalt. LÄS MER