Sökning: "AMP-activated protein kinase AMPK"
Visar resultat 1 - 5 av 18 avhandlingar innehållade orden AMP-activated protein kinase AMPK.
- Detta är en avhandling från Protein Phosphorylation, Faculty of Medicine
Sammanfattning : Abstract Along with liver and muscle tissue, adipose tissue helps maintain normal levels of glucose and lipids in the blood and has a very important role when it comes to storing lipids that can provide whole-body energy. After a meal is ingested, adipocytes take up glucose from the circulation and use it as a substrate for synthesis of new fatty acids (FAs) in a process known as de novo fatty acid synthesis, as well as for synthesis of glycerol. LÄS MER
- Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Physiology and Pharmacology
Sammanfattning : Skeletal muscle insulin resistance is a hallmark feature of Type 2 diabetes. Physical exercise/muscle contraction elicits an insulin-independent increase in glucose transport and perturbation of this pathway can bypass defective insulin signaling. LÄS MER
3. Skeletal muscle metabolic flexibility : The roles of AMP-activated protein kinase and calcineurinDetta är en avhandling från Stockholm : Karolinska Institutet, Department of Molecular Medicine and Surgery
Sammanfattning : Skeletal muscle fibers differ considerably in their metabolic and physiological properties. The metabolic properties of skeletal muscle display a high degree of flexibility which adapts to various physiological demands by shifting energy substrate metabolism. LÄS MER
- Detta är en avhandling från Department of Experimental Medical Science, Lund Univeristy
Sammanfattning : Adipose tissue does not only store and release energy in response to hormones, it is also known as an endocrine organ, secreting important factors and hormones that influence for example appetite and insulin sensitivity. The association of type 2 diabetes with obesity has been known for quite some time. LÄS MER
- Detta är en avhandling från Lund University: Faculty of Medicine
Sammanfattning : Obesity, insulin resistance and type 2 diabetes (T2D) are metabolic diseases that increase rapidly in the modern society. The underlying mechanisms are complex and involve both environmental and genetic factors. Adipose tissue is an important organ for maintaining whole body energy homeostasis. LÄS MER