Sökning: "ADC-1004"

Hittade 2 avhandlingar innehållade ordet ADC-1004.

  1. 1. Cardioprotective treatment strategies

    Författare :Jesper vanderPals; Kardiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ADC-1004; apyrase; Cardioprotection; ischemia reperfusion; hypothermia; t-PA;

    Sammanfattning : In myocardial ischemia-reperfusion (I/R) injury, complement activation, tissue plasminogen activator (t-PA) and extracellular adenosine triphosphate (ATP) release contribute to myocardial injury. ATP is degraded into adenosine by the enzyme apyrase, and adenosine possesses cardioprotective properties. LÄS MER

  2. 2. Molecular evolution of a C5aR antagonist against inflammatory disease

    Författare :Erika Gustafsson; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : New anti-inflammatory drugs with fewer adverse effects than existing drugs may prove to be useful in the treatment of several inflammatory disorders. A critical step in acute inflammation is the infiltration of neutrophils into tissues. LÄS MER