Sökning: "AChR antibody"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden AChR antibody.

1. 1. MuSK Antibody(+) Versus AChR Antibody(+) Myasthenia Gravis : Clinical, Neurophysiological and Morphological Aspects

   Författare :Anna Rostedt Punga; Erik Stålberg; Hannu Kalimo; John Newsom-Davis; Uppsala universitet; []
   Nyckelord :Neurosciences; myasthenia gravis; MuSK antibody; AChR antibody; myopathy; single-fiber EMG; mitochondria; Swedish MG questionnaire; quality of life; Neurovetenskap;

   Sammanfattning : Myasthenia gravis (MG) is an autoimmune neuromuscular disorder that causes fluctuating muscle weakness. MG may be divided into an ocular form and a generalized form based on the involved muscles. Treatment differs between these different MG forms. LÄS MER

3. 2. Studies of immune mechanisms in myasthenia gravis

   Författare :Biying Xu; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :myasthenia gravis; acetylcholine receptor; ß-adrenergic receptor; antibody; T cell receptor; antibody-dependent cell-mediated cytotoxicity; gene polymorphism;

   Sammanfattning : Myasthenia gravis (MG) has been considered the prototype of autoantibody-mediated autoimmune diseases. The pathogenic autoantibodies are directed against the acetylcholine receptor (AChR). Several mechanisms by which these antibodies (AChR Ab) disturb the function of the receptor have been elucidated. LÄS MER

4. 3. Immunochemical, biochemical and evolutionary studies on Micrurus nigrocinctus nigrocinctus venom toxins

   Författare :Alberto Alape-Girón; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Monoclonal antibody; Phospholipase A2; neurotoxin; myotoxin; protein evolution;

   Sammanfattning : Immunochemical, biochemical and evolutionary studies on Micrurus nigrocinctus nigrocinctus venom toxins Monoclonal antibodies (MAbs) were produced against venom proteins of M. nigrocinctus nigrocinctus, the medically most important elapid of Central America. LÄS MER

5. 4. T lymphocytes and cytokines in the pathogenesis of experimental autoimmune myasthenia gravis

   Författare :Guang-Xian Zhang; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Experimental autoimmune myasthenia gravis (EAMG), induced in different animal species and strains by immunization with nicotinic acetylcholine receptor (AChR) and complete Freund's adjuvant (CFA), represents an experimental model of myasthenia gravis (MG) in humans. Both MG and EAMG are autoimmune diseases mediated by antibodies against AChR of neuromuscular junctions. LÄS MER

7. 5. Immunopathogenesis and nasal tolerance in experimental autoimmune myasthenia gravis

   Författare :Fu-Dong Shi; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Myasthenia gravis (MG) is a classical antibody-mediated autoimmune disease of the neuromuscular junction. Experimental autoimmune myasthenia gravis (EAMG), can be induced in susceptible rat or mouse strains by immunization with acetylcholine receptor (AChR) in complete Freund's adjuvant (CFA). LÄS MER