Sökning: "ACTIVE-SITE"
Visar resultat 1 - 5 av 378 avhandlingar innehållade ordet ACTIVE-SITE.
1. Naphthoxylosides – Probing the β4GalT7 active site
Sammanfattning : Proteoglycans (PGs) is a class of highly anionic macromolecules that consist of one or more linear polysaccharide chains (glycosaminoglycans, GAGs) covalently attached to a core protein. The biological functions of PGs are mainly due to the interactions of GAG chains with various protein ligands and regulatory factors, such as cytokines and growth factors. LÄS MER
2. Characterization of Epoxide Hydrolases from Yeast and Potato
Sammanfattning : Epoxides are three-membered cyclic ethers formed in the metabolism of foreign substances and as endogenous metabolites. Epoxide hydrolases (EHs) are enzymes that catalyze the hydrolysis of epoxides to yield the corresponding diols. LÄS MER
3. Synthetic [FeFe] Hydrogenase Active Site Model Complexes
Sammanfattning : [FeFe]-Hydrogenases (H2ases) are metalloenzymes that can catalyze the reversible reduction of protons to molecular hydrogen as part of the metabolism of certain cyanobacteria and green algae. Due to the low availability of the enzyme, synthetic complexes that mimic the natural active site in structure, function and activity are highly sought after. LÄS MER
4. Poly(A)-Specific Ribonuclease (PARN)
Sammanfattning : Degradation of the mRNA 3'-end located poly(A) tail is an important step for mRNA decay in mammalian cells. Thus, to understand mRNA decay in detail, it is important to identify the catalytic activities involved in degrading poly(A). LÄS MER
5. Regulation of Ovarian Aromatase: Studies by Aromatase Assays in vitro and in vivo
Sammanfattning : An in vitro method was developed for measuring aromatase, based on binding of competitive aromatase inhibitor [11C]vorozole to the active site of the enzyme. [11C]Vorozole displayed high, specific binding in vitro to human placenta and human granulosa cells (GC), both fresh and frozen/thawed cells, provided correct procedures were used. LÄS MER