Sökning: "ACP"

Visar resultat 6 - 10 av 22 avhandlingar innehållade ordet ACP.

  1. 6. Zopiclone degradation in biological samples : Characteristics and consequences in forensic toxicology

    Författare :Gunnel Nilsson; Robert Kronstrand; Fredrik C. Kugelberg; Johan Ahlner; Mikael Hedeland; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Bio-analytical results are influenced by in vivo factors such as genetics, pharmacological and physiological conditions and in vitro factors such as specimen composition, sample additives and storage conditions. Zopiclone (ZOP) is a short-acting hypnotic drug (Imovane®) used for treatment of insomnia. LÄS MER

  3. 7. Biomimetic Formation of Calcium Phosphate Based Nanomaterials

    Författare :Wenxiao He; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; superstructure; lyotropic liquid crystal; self-assembly; Calcium phosphate; bone-like apatite; amphiphilic peptide; nanocomposite; biomimetic mineralization;

    Sammanfattning : The intercellular material in bone is a nanocomposite of aligned “hard” inorganics—calcium phosphate (CaP) platelets embedded in the long-range ordered “soft” organic collagen matrix. This elaborate structural arrangement redeems the weaknesses of the individual components (being soft protein or brittle mineral) and gives bone its excellent mechanical properties for the protection and support of our bodies. LÄS MER

  4. 8. Engineering central carbon metabolism with phosphoketolase pathways in Saccharomyces cerevisiae

    Författare :John Hellgren; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; precursor supply; transcriptomics; sustainability; non-oxidative glycolysis; Carbon-conservation; metabolic engineering; platform strain; GATHCYC; proteomics;

    Sammanfattning : We need more efficient biocatalysts to make sustainable microbial production of chemicals and fuels more profitable before they can replace petroleum-based sources. Rewiring the metabolic pathways in the biocatalysts to avoid the loss of carbon as CO2 can aid in improving product yields and thereby the profitability of the process. LÄS MER

  5. 9. Metabolite Profiling of Drugs using Mass Spectrometry : Identification of analytical targets for doping control and improvements of the metabolite search process

    Författare :Malin Nilsson Broberg; Mikael Hedeland; Ulf Bondesson; Curt Pettersson; Börje Tidstedt; Peter Van Eenoo; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mass spectrometry; UHPLC-HRMS; Doping control; Metabolite profile; SARM; Selective Androgen Receptor Modulator; MVDA; Microsomes; Experimental design; Analytisk farmaceutisk kemi; Analytical Pharmaceutical Chemistry;

    Sammanfattning : Doping is defined as the use of prohibited substances or methods by the World Anti-Doping Agency and the aim with doping control analysis is to detect the use of these illicit substances or methods. Substances that are prohibited in human or equine sports have either a positive or negative impact on the performance. LÄS MER

  7. 10. Evaluation of precursor and cofactor engineering strategies influencing fatty acid metabolism in Saccharomyces cerevisiae

    Författare :Alexandra Linda Bergman; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Saccharomyces cerevisiae; metabolic engineering; fatty acids; oleochemicals; NADPH; Sustainability; phosphoketolase; acetyl-CoA; transcription factor;

    Sammanfattning : If humanity is to reduce the rate of climate change, it is essential that our societies switch to a more sustainable production of fuels and chemicals, which in turn depends on technological development. Oleochemical production via microbial catalysts – such as the yeast Saccharomyces cerevisiae – can use a considerably broader range of renewable substrates compared to the conventional production processes. LÄS MER