Sökning: "ABC effect"
Visar resultat 1 - 5 av 18 avhandlingar innehållade orden ABC effect.
1. Double Pion Production in the dd to αππ reaction
Sammanfattning : The reaction dd → 4Heππ has been measured exclusively for the first time. The measurements were performed at Td = 712 MeV and Td = 1029 MeV, with the WASA detector assembly at CELSIUS (Uppsala-Sweden). The aim was to investigate a long standing puzzle, the so called ABC effect. LÄS MER
2. As simple as ABC - the dd → α X reaction explained
Sammanfattning : A model is presented for the dd → αππ reaction. It is based on two parallell and almost independent NN → dπ processes, where the final deutrons fuse to form the α particle. While underestimating the results at lower energies, the modelgives a good quantitative description of the α-particle momentum distributions throughout the 0. LÄS MER
3. In vivo Pharmacokinetics of Two New Thrombin Inhibitor Prodrugs : Emphasis on Intestinal and Hepatobiliary Disposition and the Influence of Interacting Drugs
Sammanfattning : Biliary excretion is an important elimination route for many drugs and metabolites. For such compounds, it is important to know the extent of excretion and drug exposure in the bile, e.g., for the risk assessment of drug interactions, liver toxicity and the effects of genetic variants. LÄS MER
4. Studies on surface proteins of Gram-positive bacteria
Sammanfattning : Despite the availability of antibiotics and modern health care, infectious diseases continue to cause great suffering and costs. Bacterial surface proteins are important for the interaction between host and pathogen. LÄS MER
5. Influence of CYP3A enzymes and ABC transporters on the activity of tyrosine kinase inhibitors in chronic myeloid leukemia
Sammanfattning : The introduction of imatinib, a tyrosine kinase inhibitor (TKI), in the treatment of chronic myeloid leukemia (CML) was a major break-through and the first drug that was successfully designed to target the specific mechanism of a malignant disease. Imatinib still remains as the standard treatment of newly diagnosed CML patients although a second generation of TKIs has also been approved for first-line CML treatment. LÄS MER