Sökning: "A1m"
Visar resultat 1 - 5 av 15 avhandlingar innehållade ordet A1m.
1. A1M as a Radioprotector of the Kidneys
Sammanfattning : .... LÄS MER
2. A1M: a heme and radical binding protein. A study on structure, function and mechanisms
Sammanfattning : This thesis describes functional and structural studies of the human protein α1-microglobulin (A1M), an evolutionarily well-conserved 26 kDa plasma and tissue protein mainly synthesized in the liver. A1M belongs to the lipocalin protein family. Lipocalins share a very similar structur, an 8-stranded β-barrel forming a hydrophobic pocket. LÄS MER
3. Urinary Clara cell protein and alpha 1-microglobulin – biomarkers of changes in kidney and airway function
Sammanfattning : Validated biomarkers are useful tools for screening large populations. The benefit of screening may be improved risk assessment or early indications of adverse effects before detection or onset of symptoms. LÄS MER
4. Alpha-1-microglobulin, heme-binding protein, reductase and antioxidant
Sammanfattning : This thesis describes structural and functional studies of alpha-1-microglobulin (a1m), a 26 kDa plasma and tissue protein that is evolutionarily well-conserved and belongs to the lipocalin superfamily. The lipocalins are polypeptides of 160-190-amino acids that are folded into an 8-stranded beta-barrel forming a pocket with a hydrophobic interior. LÄS MER
5. α1-microglobulin – Therapeutic opportunities in kidney and erythrocyte pathology
Sammanfattning : Oxidative stress is defined as an imbalance between oxidants and antioxidants. The reasons behind the condition are diverse, and can result in, or contribute to, the severity of many diseases. The body has different protective mechanisms to reduce the oxidative burden, among them a protein called α1-microglobulin (A1M). LÄS MER