Sökning: "A-to-I editing"

Visar resultat 11 - 15 av 15 avhandlingar innehållade orden A-to-I editing.

1. 11. The multi-faceted RNA molecule : Characterization and Function in the regulation of Gene Expression

   Författare :Mats Ensterö; Marie Öhman; Jørgen Kjems; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Computational Biology; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

   Sammanfattning : In this thesis I have studied the RNA molecule and its function and characteristics in the regulation of gene expression. I have focused on two events that are important for the regulation of the transcriptome: Translational regulation through micro RNAs; and RNA editing through adenosine deaminations. LÄS MER

3. 12. Taking advantage of phylogenetic trees in comparative genomics

   Författare :Örjan Åkerborg; Jens Lagergren; Mathieu Blanchette; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Computer Science; Bioinformatics; Bioinformatik;

   Sammanfattning : Phylogenomics can be regarded as evolution and genomics in co-operation. Various kinds of evolutionary studies, gene family analysis among them, demand access to genome-scale datasets. But it is also clear that many genomics studies, such as assignment of gene function, are much improved by evolutionary analysis. LÄS MER

4. 13. Molecular dynamics simulations of RNA bulges, loops and base flipping

   Författare :Boel Nyström Macchion; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : RNA molecules have several important functions in a cell. They carry the genetic information from DNA to protein, act as catalysts and regulate gene expression. Both DNA and RNA consist of nucleotides, DNA molecules are mainly double stranded while RNA molecules often have single stranded regions that interrupt the double stranded structure. LÄS MER

5. 14. RNA-based spatial characterization of cell and tissue heterogeneity

   Författare :Elin Lundin; Mats Nilsson; Rickard Sandberg; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Padlock probes; in situ sequencing; single cell resolution; single nucleotide variant resolution; spatial transcription profiling; Biochemistry; biokemi;

   Sammanfattning : Technical advances in cell biology have revolutionized the field of cell biology. With new technology it is now possible to address scientific questions in cell biology at the molecular level. LÄS MER

7. 15. Exploring the transcriptome of the brain

   Författare :Allissa Dillman; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Our knowledge of the transcriptome has become much more complex since the days of the central dogma of molecular biology. We now know that splicing takes place to create potentially thousands of isoforms from a single gene, and we know that RNA does not always faithfully recapitulate DNA if RNA editing occurs. LÄS MER