Sökning: "A A Mathe"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden A A Mathe.

  1. 1. P-glycoprotein and chiral antidepressant drugs : Pharmacokinetic, pharmacogenetic and toxicological aspects

    Författare :Louise Karlsson; Fredrik C. Kugelberg; Finn Bengtsson; Johan Ahlner; Aleksander A. Mathé; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : The blood-brain barrier (BBB) is formed by the capillary endothelial cells, joined together by tight junctions, with transporter proteins. BBB acts to regulate the brain concentrations of substances including many drugs. LÄS MER

  3. 2. Mapping the Landscape of Digital Game-Based Learning in Swedish Compulsory and Upper Secondary Schools : Opportunities and Challenges for Teachers

    Författare :Melinda Máthé; Harko Verhagen; Mats Wiklund; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; digital game-based learning; digital game-based teaching; digital games; education and games; Information Society; informationssamhället;

    Sammanfattning : Interest in the use of digital games in education has been increasing over the past few decades. Advocates argue that digital games are powerful learning tools with the potential to support increased motivational, cognitive, behavioural, affective, physiological and social outcomes. However, empirical evidence for their effectiveness is mixed. LÄS MER

  4. 3. The phencyclidine model of schizophrenia : dysregulation of brain dopamine systems induced by NMDA receptor antagonists

    Författare :Jan M Mathé; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :phencyclidine; MK-801; CNQX; prazosin; tetrodotoxin; dopamine; neurotensin; ventral tegmental area; nucleus accumbens; medial prefrontal cortex;

    Sammanfattning : Non-competitive NMDA receptor antagonists, such as phencyclidine (PCP) and dizocilpine (MK-801) can even acutely induce a drug induced psychotic state which closely resembles schizophrenia. The midbrain dopamine (DA) neurons, which originate in the ventral tegmental area (VTA), are involved in motivational, attentional and cognitive processes, and have also been profoundly implicated in schizophrenia. LÄS MER

  5. 4. Rätt mätt på prov : Om validering av bedömningar i skolan

    Författare :Peter Nyström; Widar Henriksson; Gunnar Gjone; Umeå universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Education; Pedagogik; bedömning; validitet; läroplan; kunskapssyn; Education; Pedagogik; Education; pedagogik;

    Sammanfattning : The thesis focuses on validation as a process whereby the quality of educational assessments can be evaluated. On the basis of Messick’s (1989) validity concept, which takes consequences as well as inferences of assessment results into account, a model for validation is described. LÄS MER

  7. 5. Network Optimization of Evolving Mobile Systems with Presence of Interference Coupling

    Författare :Lei You; Di Yuan; Pierre Flener; Gabor Fodor; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Resource optimization; load coupling; OFDMA; NOMA; Computer Science; Datavetenskap;

    Sammanfattning : The rapid development from 4G to 5G of mobile communications poses significant challenges in providing high rate and capacity, making it more crucial for efficient utilization of time-frequency resource via optimally configuring the network. Mathematical optimization serves as a powerful tool for addressing this type of problems. LÄS MER