Sökning: "68Ga"
Visar resultat 1 - 5 av 29 avhandlingar innehållade ordet 68Ga.
1. Synthesis, Characterisation and Application of 68Ga-labelled Macromolecules
Sammanfattning : The positron emitting radionuclide 68Ga (T1/2 = 68 min) might become of practical interest for clinical positron emission tomography (PET). The metallic cation, 68Ga(III), is suitable for complexation with chelators, either naked or conjugated with biological macromolecules. LÄS MER
2. Development of 18F- and 68Ga-Labelled Tracers : Design Perspectives and the Search for Faster Synthesis
Sammanfattning : This thesis deals with the design of 18F- and 68Ga-labelled positron emission tomography (PET) tracers and the development of technologies that enable faster and simpler preparation with high specific radioactivity. Techniques like microwave heating and reducing the concentrations of the precursor were investigated with this perspective. LÄS MER
3. Labelling of various macromolecules using positron emitting 76Br and 68Ga : Synthesis and characterisation
Sammanfattning : Different prosthetic groups containing a trialkylstannyl- and an electrophilic group have been synthesised and labelled with the accelerator produced 76Br (T1/2=16 h) through oxidative bromination. The labelled prosthetic groups were conjugated to amino-containing macromolecules such as proteins and 5´-modified oligonucleotides. LÄS MER
4. Pituitary Tumors - Epidemiology and the Diagnostic Value of 68Ga-DOTATOC PET
Sammanfattning : Pituitary neuroendocrine tumors (PitNETs) are considered common in the general population. However benign in most cases, these tumors can evoke dramatic morbidity in patients with aggressive tumor growth and/or excess hormone secretion. LÄS MER
5. [68Ga]Exendin-4: Bench-to-Bedside : PET molecular imaging of the GLP-1 receptor for diabetes and cancer
Sammanfattning : Diabetes epidemic is underway. Beta cell dysfunction (BCF) and loss of beta cell mass (BCM) are known to be key events in its progression. Currently, there are no reliable techniques to estimate or follow the loss of BCM, in vivo. LÄS MER