Sökning: "5alpha-androstane-3beta"

Hittade 3 avhandlingar innehållade ordet 5alpha-androstane-3beta.

1. 1. Nuclear receptor functions in the central nervous system : clues from knockout mice

   Författare :Sandra Andersson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Estrogen receptor; liver X receptor; 5alpha-androstane-3beta; 17beta-diol; brain development; neuronal degeneration; spinal cord; motor neuron.;

   Sammanfattning : The nuclear receptor (NR) superfamily is the largest known family of transcription factors in eukaryotes. In the 1980 s when the size of the NR family and the scope of the functions of its members were being discovered, tissue distribution studies revealed that the mRNAs of many of these receptors were expressed in the central nervous system. LÄS MER

3. 2. Role of estrogen receptor beta in mouse prostate and bladder with references to human diseases

   Författare :Otabek Imamov; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : After the discovery of estrogen receptor beta (ERbeta) in 1995, it became clear that in many non-classical estrogen-responsive organs, were in fact direct targets for estrogen. One of these organs is prostate gland, where ERbeta is abundant in epithelium. LÄS MER

4. 3. Growth factors in spermatogenesis

   Författare :Aida Wahlgren; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Testis; seminiferous tubules; proliferation; growth factors; sex steroids;

   Sammanfattning : The aim of this study was to increase the knowledge of die effects of locally produced growth factors and hormones on germ cell proliferation in rat testis in vitro. Since impaired sperm production and function accounts for half the cases of infertility, it is important to understand the physiological actions in germ cell development. LÄS MER