Sökning: "5-LO"
Visar resultat 16 - 20 av 22 avhandlingar innehållade ordet 5-LO.
16. Leukotriene C4 synthesis and export in human platelets and leukocytes : LTC4 synthase expression in normal and leukemic myeloid cells
Sammanfattning : Leukotriene (LT)C4 synthase catalyses conjugation of the unstable epoxide LTA4 with reduced glutathione and is the rate-limiting enzyme in the formation of cysteinyl leukotrienes, powerful mediators of asthma and inflammation. The presence of LTC4 synthase in platelets was demonstrated by purification and characterization of bovine platelet LTC4 synthase. LÄS MER
17. Persistent inflammatory pathways in rheumatoid arthritis despite anti-rheumatic treatment
Sammanfattning : The past years have witnessed tremendous progress in the treatment of rheumatoid arthritis, a chronic debilitating autoimmune disease mainly characterized by joint inflammation with progressive tissue destruction and loss of function. This condition affects 0. LÄS MER
18. Polymyositis and dermatomyositis : inflammation, muscle structure and immunosuppressive treatment
Sammanfattning : Polymyositis and dermatomyositis are chronic, inflammatory disorders characterized by muscle weakness, low muscle endurance and by inflammation in skeletal muscle tissues. The pathogenesis is not completely understood and several mechanisms are believed to be involved. LÄS MER
19. Eicosanoids and exosomes : a link between macrophages and lung cancer
Sammanfattning : Chronic inflammation increases the risk of lung cancer. Macrophages (MO) are important players in inflammation, with regulatory and executive functions. Eicosanoids and exosomes can be both triggers and mediators of these functions. LÄS MER
20. Radiation-induced vascular inflammation : translational studies
Sammanfattning : Radiotherapy has been shown to increase the risk for localized cardiovascular disease in a growing population of cancer survivors. However, irradiation, as a risk factor for vascular complications in free flap surgery, has been debated. LÄS MER
